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肥胖症手术患者的精神障碍共病情况及其与饮食失调的关联:一项基于结构化访谈诊断的横断面研究。

Psychiatric disorder comorbidity and association with eating disorders in bariatric surgery patients: A cross-sectional study using structured interview-based diagnosis.

作者信息

Rosenberger Patricia H, Henderson Kathryn E, Grilo Carlos M

机构信息

Department of Epidemiology & Public Health, Yale University School of Medicine, New Haven, CT 06519, USA.

出版信息

J Clin Psychiatry. 2006 Jul;67(7):1080-5. doi: 10.4088/jcp.v67n0710.

Abstract

OBJECTIVE

This study examined the prevalence of DSM-IV Axis I psychiatric disorders in severely obese bariatric surgery candidates and explored whether eating disorders were associated with psychiatric comorbidity.

METHOD

The Structured Clinical Interview for DSM-IV Axis I Disorders was administered to a study group of 174 consecutively evaluated bariatric surgery candidates. All evaluations were completed between September 2002 and November 2004.

RESULTS

Overall, 36.8% of the participants met criteria for at least one lifetime psychiatric disorder, with 24.1% meeting criteria for a current disorder. The most commonly observed lifetime psychiatric diagnoses were affective disorders (22.4%), anxiety disorders (15.5%), and eating disorders (13.8%). Participants with eating disorders were significantly more likely than those without eating disorders to meet criteria for psychiatric disorders overall (66.7% vs. 26.7%) and specifically for anxiety disorders (45.8% vs. 10.7%).

CONCLUSIONS

Psychiatric disorders are not uncommon among severely obese patients who present for bariatric surgery. The observed prevalence rates based on structured diagnostic interviews are lower than previously reported based on questionnaire, clinical, and chart review methods but are similar to those reported for nationally representative samples. Among bariatric surgery candidates, the presence of eating disorders is associated with higher rates of other psychiatric disorders. The findings highlight the importance of systematic diagnostic assessment using a structured diagnostic interview for determining the full spectrum of Axis I disorders.

摘要

目的

本研究调查了严重肥胖的减肥手术候选者中《精神疾病诊断与统计手册》第四版(DSM-IV)轴I精神障碍的患病率,并探讨饮食失调是否与精神疾病共病有关。

方法

对一组174名连续接受评估的减肥手术候选者进行了DSM-IV轴I障碍的结构化临床访谈。所有评估均在2002年9月至2004年11月之间完成。

结果

总体而言,36.8%的参与者符合至少一种终生精神障碍的标准,24.1%符合当前精神障碍的标准。最常观察到的终生精神疾病诊断为情感障碍(22.4%)、焦虑障碍(15.5%)和饮食失调(13.8%)。与没有饮食失调的参与者相比,有饮食失调的参与者更有可能符合总体精神疾病标准(66.7%对26.7%),特别是焦虑障碍标准(45.8%对10.7%)。

结论

在前来接受减肥手术的严重肥胖患者中,精神疾病并不罕见。基于结构化诊断访谈观察到的患病率低于先前基于问卷、临床和病历审查方法报告的患病率,但与全国代表性样本报告的患病率相似。在减肥手术候选者中,饮食失调的存在与其他精神疾病的较高发生率相关。这些发现凸显了使用结构化诊断访谈进行系统诊断评估对于确定轴I障碍全谱的重要性。

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