Moscovici L
Department of Psychiatry, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Acta Psychiatr Scand. 2006 Sep;114(3):216-8; discussion 218-9. doi: 10.1111/j.1600-0447.2006.00844.x.
We describe a patient diagnosed as having seasonal affective disorder (SAD, winter depression), an unlikely condition in Israel (latitude 32.6 degrees N), a country with relatively minor daylight photoperiodic changes between seasons.
Case report.
A 46-year-old woman with a clinical picture of depression (Diagnostic and Statistical Manual of Mental Disorders diagnostic criteria for 'major depression with seasonal pattern') reacted positively to 3 weeks of daily bright light therapy of 10,000 lux/wide spectrum. She was asked to wear dark sunglasses during placebo sessions to accommodate an A-B-C single-case-design. The intervention resulted in an improvement of 74-80% in the Hamilton anxiety and depression scales (clinician-rated) and the Beck depression inventory, similar to results obtained in high latitude regions. The depression and anxiety levels returned close to baseline levels following 1 week of the placebo intervention.
Seasonal affective disorder is apparently not limited to certain latitudes. The effect of light therapy was short-lived after discontinuation of the treatment, with rapid relapse occurring in the placebo phase.
我们描述了一名被诊断为患有季节性情感障碍（SAD，冬季抑郁症）的患者，在以色列（北纬32.6度）这种情况不太常见，该国不同季节之间的日光光周期变化相对较小。
病例报告。
一名46岁女性，具有抑郁症的临床表现（符合《精神疾病诊断与统计手册》中“季节性模式的重度抑郁症”的诊断标准），对为期3周、每天10000勒克斯/广谱的强光疗法反应良好。在安慰剂治疗期间，要求她佩戴深色太阳镜，以适应A - B - C单病例设计。干预使汉密尔顿焦虑和抑郁量表（临床医生评定）以及贝克抑郁量表的得分改善了74% - 80%，与在高纬度地区获得的结果相似。在安慰剂干预1周后，抑郁和焦虑水平恢复到接近基线水平。
季节性情感障碍显然并不局限于某些纬度。停止治疗后，光疗法的效果是短暂的，在安慰剂阶段迅速复发。
