Busacca Mauro, Chiaffarino Francesca, Candiani Massimo, Vignali Michele, Bertulessi Carlo, Oggioni Giulia, Parazzini Fabio
Clinica Ostetrico Ginecologica, Università di Milano, Ospedale Macedonio Melloni, Milano, Italy.
Am J Obstet Gynecol. 2006 Aug;195(2):426-32. doi: 10.1016/j.ajog.2006.01.078.
This study was undertaken to analyze the frequency and the determinants of long-term clinically detectable recurrence rate of deep, ovarian, and pelvic endometriosis.
The clinical data of 1106 women with first diagnosis of endometriosis observed between 1979 and 2001 were collected.
The 4-year recurrence rate was 24.6%, 17.8%, 30.6% and 23.7%, respectively, for cases of ovarian, pelvic, deep, and ovarian and pelvic endometriosis (P < .05). The recurrence rates decreased in all groups (with the exception of ovarian endometriosis) in the class age 34 years or older, these findings were significant (P < .05). Radicality was associated with lower recurrence rates in all the groups. A pregnancy after diagnosis was associated with a reduced risk of recurrence.
The study shows that the recurrence rates of endometriosis were higher in case of deep endometriosis and that the risk factors for recurrence were similar among women with endometriosis at different sites.
本研究旨在分析深部、卵巢及盆腔子宫内膜异位症长期临床可检测复发率的频率及决定因素。
收集了1979年至2001年间首次诊断为子宫内膜异位症的1106名女性的临床资料。
卵巢、盆腔、深部以及卵巢和盆腔子宫内膜异位症患者的4年复发率分别为24.6%、17.8%、30.6%和23.7%(P < .05)。在34岁及以上年龄段,所有组(卵巢子宫内膜异位症除外)的复发率均下降,这些发现具有统计学意义(P < .05)。在所有组中,手术彻底性与较低的复发率相关。诊断后怀孕与复发风险降低相关。
该研究表明,深部子宫内膜异位症的复发率较高,且不同部位子宫内膜异位症女性的复发风险因素相似。