Kupec Tomas, Wagels Lisa, Caspers Rebecca, Meyer-Wilmes Philipp, Najjari Laila, Stickeler Elmar, Wittenborn Julia
Department of Gynecology and Obstetrics, University Hospital of the RWTH Aachen, Pauwelsstrasse 30, 52074, Aachen, Germany.
Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospital of the RWTH Aachen, Pauwelsstrasse 30, 52074, Aachen, Germany.
Arch Gynecol Obstet. 2025 May;311(5):1371-1377. doi: 10.1007/s00404-024-07878-4. Epub 2024 Dec 27.
To evaluate the main factors influencing anxiety in endometriosis patients presenting to an endometriosis centre in Germany.
One hundred and eighty-two patients were asked to complete the German version of the STAI (state anxiety and trait anxiety) questionnaire prior to examination for diagnosis and treatment of pelvic pain or suspected endometriosis. Typical endometriosis symptoms, main complaints, operations, type of endometriosis and planned treatment were analyzed as influencing factors of anxiety in endometriosis patients. We performed linear multiple regression analyses using the forward stepwise method to test which characteristics associated with endometriosis symptoms were associated with trait anxiety and state anxiety.
Analysis of the STAI results showed that higher levels of trait anxiety were found in patients with ovarian endometriosis: t (177) = 3.06, p = 0.003 and in patients with symptoms of dyspareunia: t (177) = 2.36, p < 0.020). On the other hand, patients with recurrent endometriosis showed lower levels of trait anxiety: t (177) = - 2.39, p = 0.018. Significantly higher levels of state anxiety were found in patients with persistent endometriosis: t (177) = - 2.45, p = 0.015 and in women with endometriosis who were indicated for surgical therapy: t (177) = 3.89, p < 0.001.
We were able to show that higher levels of ongoing anxiety in endometriosis patients are associated with dyspareunia and ovarian endometriosis, which may have a negative impact on partnership and desire to have children. On the other hand, patients with persistent endometriosis or a type of disease that requires surgery have higher levels of immediate situational anxiety.
评估影响到德国一家子宫内膜异位症中心就诊的子宫内膜异位症患者焦虑情绪的主要因素。
182例患者在接受盆腔疼痛或疑似子宫内膜异位症的诊断和治疗检查前，被要求完成德文版的STAI（状态焦虑和特质焦虑）问卷。分析典型的子宫内膜异位症症状、主要诉求、手术情况、子宫内膜异位症类型和计划治疗方案，作为子宫内膜异位症患者焦虑情绪的影响因素。我们采用向前逐步法进行线性多元回归分析，以检验哪些与子宫内膜异位症症状相关的特征与特质焦虑和状态焦虑有关。
对STAI结果的分析表明，卵巢子宫内膜异位症患者的特质焦虑水平较高：t(177)=3.06，p=0.003；性交困难症状患者的特质焦虑水平也较高：t(177)=2.36，p<0.020）。另一方面，复发性子宫内膜异位症患者的特质焦虑水平较低：t(177)= -2.39，p=0.018。持续性子宫内膜异位症患者的状态焦虑水平显著较高：t(177)= -2.45，p=0.015；以及被建议进行手术治疗的子宫内膜异位症女性患者的状态焦虑水平也较高：t(177)=3.89，p<0.001。
我们能够证明，子宫内膜异位症患者较高水平的持续性焦虑与性交困难和卵巢子宫内膜异位症有关，这可能对伴侣关系和生育愿望产生负面影响。另一方面，患有持续性子宫内膜异位症或需要手术治疗的疾病类型的患者，即时情境焦虑水平较高。
