Khadilkar V V, Khadilkar A V, Kinare A S, Tapasvi H S, Deshpande S S, Maskati G B
Growth and Pediatric Endocrine Unit, Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, 32, Sassoon Road, Pune 411 001, India.
Indian Pediatr. 2006 Jul;43(7):625-30.
The aim of our study was to determine the pattern of female reproductive organ growth in Indian girls from birth to 18 years of age and to correlate the uterine length, mean ovarian volume (MOV) and Fundo Cervical Ratio (FCR) with chronological age, bone age and pubertal breast staging. A cross sectional study was performed on 218 girls from birth to 18 years of age. Height, weight, stage of puberty, X-ray for bone age and transabdominal ultrasounds were performed on all girls. Higher chronological age, bone age and increase in breast stage significantly predicted higher MOV (P < 0.001) and higher uterine length (P < 0.001). The MOV, uterine length and FCR are positively correlated with chronological age, bone age, height, weight and breast staging. Data from present study may be useful in screening cases of precocious puberty and other disorders that may need further evaluation.
我们研究的目的是确定印度女孩从出生到18岁女性生殖器官的生长模式，并将子宫长度、平均卵巢体积（MOV）和宫底宫颈比（FCR）与实际年龄、骨龄和青春期乳房分期相关联。对218名从出生到18岁的女孩进行了横断面研究。对所有女孩进行了身高、体重、青春期阶段、骨龄X线检查和经腹超声检查。较高的实际年龄、骨龄和乳房分期增加显著预测了较高的MOV（P<0.001）和较高的子宫长度（P<0.001）。MOV、子宫长度和FCR与实际年龄、骨龄、身高、体重和乳房分期呈正相关。本研究的数据可能有助于筛查性早熟和其他可能需要进一步评估的疾病病例。
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