Dobreva M, Dancheva N, Holt P F
Br J Ind Med. 1975 Aug;32(3):224-7. doi: 10.1136/oem.32.3.224.
Poly(2-vinylpyridine 1-oxide) inhibits the cytotoxic effects of quartz in cell cultures but the syndiotactic polymer behaves differently from the isotactic and atactic polymers. In each case approximately 1-0 mg/m2 of the polymer represents the adsorption maximum. No difference has been found between the adsorption isotherms of the stereoisomeric polymers or the stability of the adsorbed layers. The layers are not removed by repeated washing. The observations do not support the theory that the poly(2-vinylpyridine 1-oxide) is active because it coats the quartz surface.
聚(2-乙烯基吡啶1-氧化物)可抑制石英在细胞培养中的细胞毒性作用,但间同立构聚合物的行为与等规和无规聚合物不同。在每种情况下,聚合物约1.0毫克/平方米代表最大吸附量。立体异构聚合物的吸附等温线或吸附层的稳定性之间未发现差异。通过反复洗涤不会去除这些层。这些观察结果不支持聚(2-乙烯基吡啶1-氧化物)因其覆盖石英表面而具有活性的理论。