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间同立构和全同立构聚（2-乙烯基吡啶1-氧化物）在石英表面的吸附

Adsorption of syndiotactic and isotactic poly(2-vinylpyridine 1-oxide) on quartz surface.

作者信息

Dobreva M, Dancheva N, Holt P F

出版信息

Br J Ind Med. 1975 Aug;32(3):224-7. doi: 10.1136/oem.32.3.224.

DOI:10.1136/oem.32.3.224
PMID:168917
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1008063/
Abstract

Poly(2-vinylpyridine 1-oxide) inhibits the cytotoxic effects of quartz in cell cultures but the syndiotactic polymer behaves differently from the isotactic and atactic polymers. In each case approximately 1-0 mg/m2 of the polymer represents the adsorption maximum. No difference has been found between the adsorption isotherms of the stereoisomeric polymers or the stability of the adsorbed layers. The layers are not removed by repeated washing. The observations do not support the theory that the poly(2-vinylpyridine 1-oxide) is active because it coats the quartz surface.

摘要

聚（2-乙烯基吡啶1-氧化物）可抑制石英在细胞培养中的细胞毒性作用，但间同立构聚合物的行为与等规和无规聚合物不同。在每种情况下，聚合物约1.0毫克/平方米代表最大吸附量。立体异构聚合物的吸附等温线或吸附层的稳定性之间未发现差异。通过反复洗涤不会去除这些层。这些观察结果不支持聚（2-乙烯基吡啶1-氧化物）因其覆盖石英表面而具有活性的理论。

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Adsorption of syndiotactic and isotactic poly(2-vinylpyridine 1-oxide) on quartz surface.间同立构和全同立构聚（2-乙烯基吡啶1-氧化物）在石英表面的吸附
Br J Ind Med. 1975 Aug;32(3):224-7. doi: 10.1136/oem.32.3.224.
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[Effect of polyvinylpyridine N-oxide on the elimination from the lungs of radioactive cobalt particles which have entered separately and together with quartz dust].[聚维酮N-氧化物对单独进入以及与石英粉尘一起进入肺部的放射性钴颗粒从肺中清除的影响]
Farmakol Toksikol. 1974 Nov-Dec;37(6):729-33.

引用本文的文献

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Protective effect of poly-2-vinylpyridine-N-oxide on susceptibility of silica-treated mice to experimental histoplasmosis.聚-2-乙烯基吡啶-N-氧化物对经二氧化硅处理的小鼠实验性组织胞浆菌病易感性的保护作用。
Infect Immun. 1983 Nov;42(2):818-23. doi: 10.1128/iai.42.2.818-823.1983.
2
Counteraction of poly(4-vinylpyridine-n-oxide) on the depression of viral interferon induction by coal dust.聚（4-乙烯基吡啶氮氧化物）对煤尘抑制病毒干扰素诱导的对抗作用。
Infect Immun. 1976 May;13(5):1334-42. doi: 10.1128/iai.13.5.1334-1342.1976.

本文引用的文献

1
[Inhibition of experimental silicosis by subcutaneous administration of polyvinylpyridine-N-oxide].[皮下注射聚乙烯吡啶-N-氧化物对实验性矽肺的抑制作用]
Klin Wochenschr. 1961 Nov 15;39:1182-9. doi: 10.1007/BF01532453.
2
[Alteration of the cytotoxic effect of quartz on mouse fibroblasts (strain L) by polyvinylpyridine-N-oxide].[聚乙烯吡啶-N-氧化物对石英对小鼠成纤维细胞（L株）细胞毒性作用的改变]
Z Zellforsch Mikrosk Anat. 1963;59:568-76.
3
Poly(vinylpyridine oxides) in pneumoconiosis research.聚（乙烯基吡啶氧化物）在尘肺病研究中的应用
Br J Ind Med. 1971 Jan;28(1):72-7. doi: 10.1136/oem.28.1.72.
4
Some derivatives of polyvinylpyridine 1-oxides and their effect on the cytotoxicity of quartz in macrophage cultures.聚乙烯基吡啶1-氧化物的一些衍生物及其对巨噬细胞培养物中石英细胞毒性的影响。
Br J Pharmacol. 1970 Jan;38(1):192-201. doi: 10.1111/j.1476-5381.1970.tb10347.x.

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