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良性幽门狭窄和胃出口梗阻的内镜治疗

Endoscopic therapy of benign pyloric stenosis and gastric outlet obstruction.

作者信息

Yusuf Tony E, Brugge William R

机构信息

GI Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.

出版信息

Curr Opin Gastroenterol. 2006 Sep;22(5):570-3. doi: 10.1097/01.mog.0000239874.13867.41.

Abstract

PURPOSE OF REVIEW

To examine the short and long-term success rates of balloon dilation of pyloric stenosis.

RECENT FINDINGS

Several large studies have demonstrated high rates of success for the relief of symptoms from pyloric stenosis using through-the-scope balloons. These dilating balloons readily increase the diameter of the stenotic pylorus on average from 6 to 16 mm. Patients who require more than two dilations are at high risk of endoscopic failure and the need for surgical intervention. Rapid re-stenosis rates are observed in patients with malignant pyloric obstruction. Since many patients with benign pyloric stenosis have underlying ulcer disease, helicobacter infection is a relatively common finding. Eradication of this infection at the time of balloon dilation will ensure higher long-term success rates.

SUMMARY

In summary, benign pyloric stenosis can be readily treated with endoscopic balloon dilation and should be the first-line therapy.

摘要

综述目的

探讨幽门狭窄球囊扩张术的短期和长期成功率。

最新研究结果

多项大型研究表明,使用经内镜球囊治疗幽门狭窄缓解症状的成功率很高。这些扩张球囊平均可使狭窄幽门的直径从6毫米轻松增加到16毫米。需要进行两次以上扩张的患者内镜治疗失败及需要手术干预的风险较高。恶性幽门梗阻患者观察到快速再狭窄率。由于许多良性幽门狭窄患者存在潜在的溃疡病,幽门螺杆菌感染是相对常见的发现。在球囊扩张时根除这种感染将确保更高的长期成功率。

总结

总之,良性幽门狭窄可通过内镜球囊扩张轻松治疗,应作为一线治疗方法。

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