Noor Mohd Talha, Dixit Pankaj, Kochhar Rakesh, Nagi Birinder, Dutta Usha, Singh Kartar, Poornachandra Kuchhangi Suresh
Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India.
Diagn Ther Endosc. 2011;2011:967957. doi: 10.1155/2011/967957. Epub 2011 Jun 6.
Endoscopic balloon dilatation (EBD) has important role in the management of benign gastric outlet obstruction. Although there are many reports on the role of EBD in the management of corrosive-induced and peptic benign GOO, there is scanty data on its role in the management of NSAID-induced GOO. We report 10 cases of NSAID-induced pyloroduodenal obstruction and their endoscopic management. The most common site of involvement was duodenum (5/10) followed by both pylorus and duodenum (4/10) and pylorus (1/10). Most of the strictures were short web-like, and the mean (SD) number of stricture was 2.0 (0.94). Endoscopic balloon dilatation was successful in 90% (9/10) cases requiring mean (SD) of 2.0 (1.6) sessions of dilatation to achieve target diameter of 15 mm and mean (SD) of 5.3 (2.7) sessions to maintain it over a treatment period of 4.5 months (IQR 2-15 months). There was no procedure-related complication or mortality.
内镜下球囊扩张术（EBD）在良性胃出口梗阻的治疗中具有重要作用。尽管有许多关于EBD在腐蚀性和消化性良性胃出口梗阻治疗中作用的报道，但关于其在非甾体抗炎药（NSAID）诱导的胃出口梗阻治疗中作用的数据却很少。我们报告了10例NSAID诱导的幽门十二指肠梗阻及其内镜治疗情况。最常受累的部位是十二指肠（5/10），其次是幽门和十二指肠均受累（4/10）以及幽门（1/10）。大多数狭窄为短网状，狭窄的平均（标准差）数量为2.0（0.94）。在需要平均（标准差）2.0（1.6）次扩张以达到15毫米目标直径且在4.5个月（四分位间距2 - 15个月）的治疗期内平均（标准差）5.3（2.7）次扩张以维持该直径的90%（9/10）病例中，内镜下球囊扩张术取得成功。没有与操作相关的并发症或死亡。
