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[热球子宫内膜消融系统治疗异常子宫出血的临床分析]

[Clinical analysis of abnormal uterine bleeding treatment with Thermablate EAS].

作者信息

Feng Li-min, Gao Wan-li, Yang Bao-jun, Wang Wei-juan, Zhao Wei-hong, Wei Li-hui

机构信息

Department of Gynecology, Peking University People's Hospital, Beijing 100044, China.

出版信息

Beijing Da Xue Xue Bao Yi Xue Ban. 2006 Aug 18;38(4):432-5.

Abstract

OBJECTIVE

To study the two-year follow-up and contrast research for 182 patients by Thermablate EAS Uterine Balloon Therapy (UBT) or Transcervical Resection of Endometrium (TCRE).

METHODS

We followed up 90 cases of UBT and 92 cases of TCRE between Oct. 2003 and June 2005. The mean age of UBT group was 49.4+/-9.4 (34-81) years, and that of TCRE group 46.6 +/-8.4 (35-74) years. The mean following-up for UBT group was 17.3+/- 5.0 (6-27) months, and that of TCRE group 17.5+/-4.1 (6-27) months. There was no noticeable difference of the high risk for complication between the two groups. The follow up happens twice a year one month after the operation. The follow up started in Dec. 2005.

RESULTS

The chi(2) value of pain during operation between two groups is 12.744. The P value is 0.000. It has statistical significance. The pain of UBT group is heavier than TCRE. The chi(2) value of blood disappearance between two groups is 24.347. The P value is 0.000. It has statistical significance. The duration of the blood disappearance of UBT group is shorter than TCRE. The chi(2) value of discharge disappearance between two groups is 99.486. The P value is 0.000. It has statistical significance. The duration of the blood discharge of UBT group is shorter than TCRE. The chi(2) value of blood flow for two years after surgery between two groups is 4.708. The P value is 0.03. It has statistical significance. The blood flow of UBT group is much more decrease than TCRE. The chi(2) value of dysmenorrheal improved after surgery between two groups is 9.970. The P value is 0.002. It has statistical significance. The dysmenorrheal improved of UBT group is much better than TCRE.

CONCLUSION

Thermablate EAS UBT is a new generation of endometrial ablation. Two years clinical observation shows that pain can be controlled by oral medicine for UBT group. The blood and discharge disappearance of UBT group is shorter than TCRE. Two years after the surgery the improvement of blood flow and dysmenorrheal released is much better than TCRE. However it probably will take longer time to show its long term effectiveness.

摘要

目的

对182例接受Thermablate EAS子宫球囊治疗(UBT)或经宫颈子宫内膜切除术(TCRE)的患者进行为期两年的随访及对比研究。

方法

2003年10月至2005年6月期间,我们对90例UBT患者和92例TCRE患者进行了随访。UBT组的平均年龄为49.4±9.4(34 - 81)岁,TCRE组为46.6±8.4(35 - 74)岁。UBT组的平均随访时间为17.3±(5.0)(6 - 27)个月,TCRE组为17.5±4.1(6 - 27)个月。两组间并发症高风险无显著差异。术后每年随访两次,术后1个月开始首次随访。随访于2005年12月开始。

结果

两组术中疼痛的卡方值为12.744,P值为0.000,具有统计学意义。UBT组的疼痛比TCRE组更严重。两组间出血消失情况的卡方值为24.347,P值为0.000,具有统计学意义。UBT组出血消失的持续时间比TCRE组短。两组间分泌物消失情况的卡方值为99.486,P值为0.000,具有统计学意义。UBT组血性分泌物持续时间比TCRE组短。两组术后两年血流量的卡方值为4.708,P值为0.03,具有统计学意义。UBT组血流量下降幅度比TCRE组大得多。两组术后痛经改善情况 的卡方值为9.970,P值为0.002,具有统计学意义。UBT组痛经改善情况比TCRE组好得多。

结论

Thermablate EAS UBT是新一代的子宫内膜消融术。两年的临床观察表明,UBT组的疼痛可用口服药物控制。UBT组出血和分泌物消失时间比TCRE组短。术后两年,血流量改善及痛经缓解情况比TCRE组好得多。然而,可能需要更长时间才能显示其长期疗效。

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