Assaad Jean-Marc, Pihl Robert O, Séguin Jean R, Nagin Daniel S, Vitaro Frank, Tremblay Richard E
Research Unit of Children's Psycho-Social Maladjustment, University of Montreal, Montreal, PQ, Canada.
Exp Clin Psychopharmacol. 2006 Aug;14(3):377-88. doi: 10.1037/1064-1297.14.3.377.
This study examined the association between the heart rate (HR) response to alcohol intoxication, which is thought to reflect sensitivity to alcohol-induced reward and alcohol-induced behavioral disinhibition. High- and low-HR responders to alcohol participated in a go/no-go task, under sober and intoxicated conditions. Errors of commission on this task have previously been related to behavioral disinhibition. High-HR responders made more intoxicated commission errors as compared with low-HR responders. High-HR responders also reported increased alcohol consumption, and controlling for the latter did not alter the significant association between high-HR responders and increased intoxicated errors of commission. These results are consistent with previous findings of an increased risk for addictive and disinhibited behavioral propensities in individuals with a high-HR response to alcohol intoxication.
本研究考察了对酒精中毒的心率（HR）反应之间的关联，这种反应被认为反映了对酒精诱导的奖赏和酒精诱导的行为去抑制的敏感性。对酒精反应高心率和低心率的参与者在清醒和醉酒状态下参与了一项停止信号任务。此前该任务中的错误执行与行为去抑制有关。与低心率反应者相比，高心率反应者在醉酒状态下出现更多的错误执行。高心率反应者还报告饮酒量增加，而控制饮酒量并未改变高心率反应者与醉酒状态下错误执行增加之间的显著关联。这些结果与之前的研究结果一致，即对酒精中毒反应高心率的个体成瘾和行为去抑制倾向增加的风险更高。
