Cimiotti Jeannie P, Haas Janet, Saiman Lisa, Larson Elaine L
Center for Health Outcomes and Policy Research, School of Nursing, University of Pennsylvania, Philadelphia, 19104-6096, USA.
Arch Pediatr Adolesc Med. 2006 Aug;160(8):832-6. doi: 10.1001/archpedi.160.8.832.
To examine the association between registered nurse staffing and healthcare-associated bloodstream infections in infants in the neonatal intensive care unit (NICU).
Prospective cohort study.
Two level III-IV NICUs in New York, NY, from March 1, 2001, through January 31, 2003.
A total of 2675 infants admitted to the NICUs for more than 48 hours and all registered nurses who worked in the same NICUs during the study period. Intervention Hours of care provided by registered nurses. Main Outcome Measure Time to first episode of healthcare-associated bloodstream infection.
A total of 224 infants had an infection that met the study definition of healthcare-associated bloodstream infection. In a multivariate analysis, after controlling for infants' intrinsic and extrinsic risk factors, a greater number of hours of care provided by registered nurses in NICU 2 was associated with a decreased risk of bloodstream infection in these infants (hazard ratio, 0.21; 95% confidence interval, 0.06-0.79).
Our findings suggest that registered nurse staffing is associated with the risk of bloodstream infection in infants in the NICU.
探讨新生儿重症监护病房（NICU）中注册护士配备与婴儿医疗相关血流感染之间的关联。
前瞻性队列研究。
纽约市的两家Ⅲ - Ⅳ级NICU，时间跨度为2001年3月1日至2003年1月31日。
共有2675名入住NICU超过48小时的婴儿，以及在研究期间于同一NICU工作的所有注册护士。干预措施：注册护士提供的护理时长。主要结局指标：首次发生医疗相关血流感染的时间。
共有224名婴儿发生了符合医疗相关血流感染研究定义的感染。在多变量分析中，在控制了婴儿的内在和外在风险因素后，NICU 2中注册护士提供的护理时长增加与这些婴儿血流感染风险降低相关（风险比，0.21；95%置信区间，0.06 - 0.79）。
我们的研究结果表明，NICU中注册护士的配备与婴儿血流感染风险相关。
