Sadjadpour K
Brain Res. 1975 Sep 23;95(2-3):403-6. doi: 10.1016/0006-8993(75)90117-1.
Certain postfacial palsy phenomena--'facial contracture', 'crocodile tears', etc.--have been examined in relation to faulty misrouting of the nerve fibers, which thus far has been offered as an explanation for such phenomena. Analogy is made with the problem of hemifacial spasm, occurring without antecedant facial palsy. It is seen that the two conditions have many things in common and are amenable to similar methods of therapy--such as surgical decompression of the facial nerve without interrupting its fibers or by pharmacological blocking of the facial nerve. Evidence is presented to support the thesis that both the hemifacial spasm and the postfacial palsy phenomena (and a number of other neurological disorders) are due to formation of an 'artificial synapse' (an ephapse) at the site of nerve injury. This would allow for crossing over of impulses from one nerve fiber to another and interaction between afferent and efferent axons, analogous to the situation of bare, uninsulated electrical wires plac
某些面瘫后现象——“面部挛缩”、“鳄鱼泪”等——已被研究，其与神经纤维的错误错向有关，迄今为止，这一直被用作对此类现象的一种解释。文中将其与无先前面瘫而发生的半面痉挛问题进行了类比。可以看出，这两种情况有许多共同之处，并且适合采用类似的治疗方法——例如对面神经进行手术减压而不切断其纤维，或者通过对面神经进行药物阻断。文中提供了证据来支持这样的论点，即半面痉挛和面瘫后现象（以及一些其他神经系统疾病）都是由于在神经损伤部位形成了“人工突触”（ephapse）。这将允许冲动从一根神经纤维交叉到另一根神经纤维，并使传入和传出轴突之间相互作用，类似于裸露、无绝缘的电线的情况。
