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微血管减压术治疗面肌痉挛后迟发性面瘫的发生率及预后

Frequency and prognosis of delayed facial palsy after microvascular decompression for hemifacial spasm.

作者信息

Rhee D J, Kong D S, Park K, Lee J A

机构信息

Deparment of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

出版信息

Acta Neurochir (Wien). 2006 Aug;148(8):839-43; discussion 843. doi: 10.1007/s00701-006-0847-9. Epub 2006 Jun 29.

Abstract

BACKGROUND

Microvascular decompression (MVD) for hemifacial spasm (HFS) provides a long-term cure rate. Delayed facial palsy (DFP) is not an unusual complication, but it has only been sporadically described in the literature. The purpose of this report is to evaluate the incidence of delayed facial palsy after MVD and its clinical course and final results.

METHODS

From January, 1998 to April, 2004, 410 patients underwent microvascular decompression for hemifacial spasm at our Institute. During this time, 21 patients (5.4%) developed delayed facial weakness; eighteen of them were given steroid medication and they were followed up in the out-patient clinic.

FINDINGS

Twenty-one patients developed DFP after microvascular decompression an incidence of 5.4%. There were seventeen women (81.0%) among the 21 patients with DFP who were included in this study. In twenty of them, the symptoms of HFS improved completely after the operation, but the spasm remained with one of them. The onset of palsy occurred between postoperative day 7 and 23 (average: 12.1 days). The palsy was at least Grade II or worse on the House-Brackmann (HB) scale. The time to recovery averaged 5.7 weeks (range: 25 days-17 weeks); 20 patients improved to complete recovery and 1 patient remained with minimal weakness, as Grade II on the HB scale, at the follow-up examination.

CONCLUSION

Our findings demonstrated that the incidence of DFP was not so low as has been reported the literature, and it did not have any striking predisposing factors. Even though the degree of facial palsy was variable, almost all patients exhibited a complete recovery without any further special treatment. The etiology of DFP and its association with herpes infection should be further clarified.

摘要

背景

微血管减压术(MVD)治疗面肌痉挛(HFS)可实现长期治愈率。迟发性面瘫(DFP)并非罕见并发症,但在文献中仅有零星描述。本报告旨在评估微血管减压术后迟发性面瘫的发生率、临床过程及最终结果。

方法

1998年1月至2004年4月,我院有410例患者接受了微血管减压术治疗面肌痉挛。在此期间,21例患者(5.4%)出现迟发性面部无力;其中18例接受了类固醇药物治疗,并在门诊接受随访。

结果

21例患者在微血管减压术后发生迟发性面瘫,发生率为5.4%。本研究纳入的21例迟发性面瘫患者中有17例女性(81.0%)。其中20例患者术后面肌痉挛症状完全改善,但有1例仍有痉挛。面瘫于术后第7天至第23天出现(平均:12.1天)。根据House-Brackmann(HB)分级,面瘫至少为Ⅱ级或更严重。恢复时间平均为5.7周(范围:25天至17周);20例患者恢复至完全康复,1例患者在随访检查时仍有轻微无力,为HB分级Ⅱ级。

结论

我们的研究结果表明,迟发性面瘫的发生率并不像文献报道的那么低,且没有任何明显的诱发因素。尽管面瘫程度各异,但几乎所有患者未经任何进一步特殊治疗均实现了完全康复。迟发性面瘫的病因及其与疱疹感染的关联应进一步阐明。

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