[1996 - 2003年德国一家转诊中心治疗外周动脉闭塞性疾病时大截肢、搭桥手术及经皮腔内血管成形术（PTA）的发生率]

[Incidence of major amputations, bypass procedures and percutaneous transluminal angioplasties (PTA) in the treatment of peripheral arterial occlusive disease in a German referral center 1996-2003].

作者信息

Wohlgemuth W A, Freitag M H, Wölfle K D, Bohndorf K, Kirchhof K

机构信息

Klinik für Diagnostische Radiologie und Neuroradiologie, Zentralklinikum Augsburg.

出版信息

Rofo. 2006 Sep;178(9):906-10. doi: 10.1055/s-2006-926866. Epub 2006 Aug 7.

DOI:10.1055/s-2006-926866

PMID:16894498

Abstract

PURPOSE

To determine the current incidence of major amputations, bypass procedures and percutaneous transluminal angioplasties (PTA) in a study population of patients with peripheral arterial occlusive disease in a German referral center.

MATERIALS AND METHODS

In a retrospective study, we recruited patients with peripheral arterial occlusive disease who underwent an amputation, bypass procedure, or PTA in the region of the pelvis or lower limbs between 1996 and 2003 at the Augsburg Medical Center. Patients were identified via the hospital database. This was performed with the help of the International Classification of Diseases (ICD 9 and 10), the operation code (OPS), and appropriate invoices. The incidence of PTAs was further estimated with 200 charts.

RESULTS

Of 5379 patients, 627 underwent amputation, 1832 a bypass procedure, and 2920 a PTA. The incidence of PTAs increased during the study period from 51.3/100 000/year to 64.4/100 000/year (p < 0.01), while the number of amputations and bypass procedures remained stable. The incidence of PTAs was exceeded by that of bypass procedures only in patients older than 85 years. The age of the amputees decreased during the study period from 72.2 to 70.5 years (p < 0.01). The age of patients who underwent a bypass procedure increased from 67.2 to 69.4 years, and the age of patients who underwent PTA increased from 66.3 to 69.8 years (p < 0.01). Bypass procedures and PTAs were performed in men 6.3 years earlier than in women (p < 0.01).

CONCLUSION

The result is a population-corrected need of 8.4/100 000/year major amputations, 23/100 000/year bypass procedures and 64.4/100 000/year PTAs for patients with peripheral arterial occlusive disease within the referral area of our hospital. The performance of major amputations and bypass procedures stagnates, while the incidence of PTAs is increasing.

摘要

目的

确定在德国一家转诊中心的外周动脉闭塞性疾病患者研究人群中，大截肢、搭桥手术和经皮腔内血管成形术（PTA）的当前发生率。

材料与方法

在一项回顾性研究中，我们招募了1996年至2003年期间在奥格斯堡医疗中心接受骨盆或下肢区域截肢、搭桥手术或PTA的外周动脉闭塞性疾病患者。通过医院数据库识别患者。这借助国际疾病分类（ICD 9和10）、手术编码（OPS）以及相应发票来完成。用200份病历进一步估算PTA的发生率。

结果

在5379例患者中，627例行截肢手术，1832例行搭桥手术，2920例行PTA。在研究期间，PTA的发生率从每年51.3/10万增至每年64.4/10万（p<0.01），而截肢手术和搭桥手术的数量保持稳定。仅在85岁以上患者中，搭桥手术的发生率超过了PTA的发生率。在研究期间，截肢患者的年龄从72.2岁降至70.5岁（p<0.01）。接受搭桥手术患者的年龄从67.2岁增至69.4岁，接受PTA患者的年龄从66.3岁增至69.8岁（p<0.01）。搭桥手术和PTA在男性中的实施比女性早6.3年（p<0.01）。