Mattes E, Norman P E, Jamrozik K
Department of Surgery, University of Western Australia, Australia.
Eur J Vasc Endovasc Surg. 1997 Jan;13(1):14-22. doi: 10.1016/s1078-5884(97)80045-7.
To assess temporal trends in the incidence of surgical procedures for peripheral occlusive arterial disease (POAD) and associated changes in outcome as measured by the rate of major lower limb amputations for POAD.
A retrospective descriptive population-based study was conducted of the geographically isolated population of Western Australia between 1980 and 1992.
Vascular procedures with an accompanying diagnosis of POAD were identified in a computerised system of name-identified records of all discharges from hospital for the population. These procedures were detected using relevant codes from the International Classification of Diseases and Procedures. Records of angioplasty and thrombolysis procedures were augmented by searches of hospital-based registers of invasive radiological procedures. The data for the remaining procedures were validated by a review of a random sample of medical records.
Over the 13 years of the study, rates of major amputations fell significantly for women under 70 years of age and for men under 80 years from 1983. At the same time there was a significant fall in non-amputation vascular surgery for individuals under the age of 60. In addition, rather than an overall rise in surgery there was shift away from sympathectomy and thromboendarterectomy to angioplasty and bypass surgery. Furthermore, an increasing proportion of all major amputations had a prior attempt at arterial reconstruction.
These observations suggest the decrease in major amputations for POAD may reflect a fall in the incidence of POAD, possibly aided by more effective surgery, rather than increased rates of vascular surgery.
评估外周闭塞性动脉疾病(POAD)外科手术发病率的时间趋势,以及通过POAD大下肢截肢率衡量的相关结局变化。
对1980年至1992年西澳大利亚地理上孤立的人群进行了一项基于人群的回顾性描述性研究。
在一个计算机化系统中识别伴有POAD诊断的血管手术,该系统记录了该人群所有出院患者的姓名识别记录。这些手术通过国际疾病和手术分类中的相关编码进行检测。通过搜索医院侵入性放射学手术登记册,补充血管成形术和溶栓手术的记录。其余手术的数据通过对随机抽取的病历进行审查来验证。
在研究的13年中,1983年起,70岁以下女性和80岁以下男性的大截肢率显著下降。同时,60岁以下人群的非截肢血管手术显著减少。此外,手术并非总体上升,而是从交感神经切除术和血栓内膜切除术转向血管成形术和搭桥手术。此外,所有大截肢手术中,先前尝试进行动脉重建的比例越来越高。
这些观察结果表明,POAD大截肢率的下降可能反映了POAD发病率的下降,可能得益于更有效的手术,而非血管手术率的增加。