[Management of unresectable non-metastatic non-small cell lung cancer. Guidelines of clinical practice made by the European Lung Cancer Working Party].

The present guidelines on the management of unresectable non-metastatic non-small cell lung cancer (NSCLC) were formulated by the ELCWP in October 2005. They are designed to answer the following eight questions: 1) Is chest irradiation curative for NSCLC? 2) What are the contraindications (anatomical or functional) to chest irradiation? 3) Does the addition of chemotherapy add any advantage to radiotherapy? 4) Does the addition of radiotherapy add any advantage to chemotherapy? 5) In marginally respectable stage III is irradiation as effective as surgery? 6) How to best combine chemotherapy with radiotherapy: sequentially, concomitantly, as consolidation, as induction, as radiosensitiser? 7) In case of too advanced locoregional disease, is there a role for consolidation (salvage) local treatment (surgery, radiotherapy) after induction chemotherapy? 8) In 2005, what are the technical characteristics of an adequate radiotherapy?