Rev Med Brux. 2008 May-Jun;29(3):159-67.
The present guidelines on the management of limited disease small cell lung cancer (SCLC) were formulated by the European Lung Cancer Working Party in April 2007. They are designed to answer the following seven questions: 1) What is the definition of limited disease? 2) Should chest radiotherapy be provided and what are the benefits? 3) What is the optimal timing and mode of administration of chest irradiation? 4) Which are the optimal radiotherapy parameters: dose, fractionation, target volume? 5) What is the optimal chemotherapy regimen for limited disease SCLC? 6) Should prophylactic cranial irradiation be provided, when and for which patients? 7) What is the additional role of thoracic surgery in early SCLC?
欧洲肺癌工作组于2007年4月制定了当前关于局限性小细胞肺癌(SCLC)管理的指南。这些指南旨在回答以下七个问题:1)局限性疾病的定义是什么?2)是否应进行胸部放疗,其益处有哪些?3)胸部照射的最佳时机和给药方式是什么?4)最佳放疗参数是什么:剂量、分割方式、靶区体积?5)局限性SCLC的最佳化疗方案是什么?6)是否应进行预防性颅脑照射,何时进行以及针对哪些患者?7)胸外科手术在早期SCLC中的额外作用是什么?