Calderon Rebecca L, Craun Gunther F
US Environmental Protection Agency, MD-58a, Research Triangle Park, NC 27711, USA.
J Water Health. 2006;4 Suppl 2:89-99. doi: 10.2166/wh.2006.019.
The nature and magnitude of endemic waterborne disease are not well characterized in the United States. Epidemiologic studies of various designs can provide an estimate of the waterborne attributable risk along with other types of information. Community drinking water systems frequently improve their operations and may change drinking water treatment and their major source of water. In the United States, many of these treatment changes are the result of regulations promulgated under the Safe Drinking Water Act. A community-intervention study design takes advantage of these "natural" experiments to assess changes in health risks. In this paper, we review the community-intervention studies that have assessed changes in waterborne gastroenteritis risks among immunocompetent populations in industrialized countries. Published results are available from two studies in Australia, one study in the United Kingdom, and one study in the United States. Preliminary results from two other US studies are also available. Although the current information is limited, the risks reported in these community-intervention studies can help inform the national estimate of endemic waterborne gastroenteritis. Information is provided about endemic waterborne risks for unfiltered surface water sources and a groundwater under the influence of surface water. Community-intervention studies with recommended study modifications should be conducted to better estimate the benefits associated with improved drinking water treatment.
在美国,地方性水源性疾病的性质和严重程度尚未得到充分描述。各种设计的流行病学研究可以提供水源性归因风险的估计值以及其他类型的信息。社区饮用水系统经常改进其运营,并可能改变饮用水处理方式及其主要水源。在美国,许多这些处理方式的改变是根据《安全饮用水法》颁布的法规所导致的。社区干预研究设计利用这些“自然”实验来评估健康风险的变化。在本文中,我们回顾了评估工业化国家免疫功能正常人群水源性肠胃炎风险变化的社区干预研究。已发表的结果来自澳大利亚的两项研究、英国的一项研究和美国的一项研究。另外两项美国研究的初步结果也已可得。尽管目前的信息有限,但这些社区干预研究报告的风险有助于为全国地方性水源性肠胃炎的估计提供参考。提供了关于未过滤地表水水源和受地表水影响的地下水的地方性水源性风险的信息。应开展具有推荐研究改进措施的社区干预研究,以更好地估计与改善饮用水处理相关带来的益处。