Oddó B David
Departamento de Anatomía Patológica, Pontificia Universidad Católica de Chile, Santiago, Chile.
Rev Chilena Infectol. 2006 Sep;23(3):200-14. Epub 2006 Aug 4.
Infections caused by free-living amebae constitute one of emergent opportunistic infections with greatest medical interest. Although infrequently, they have been described in almost all world, its diagnosis depends on a high index of suspicion, especially in morpho-pathologic and laboratory studies. Exciting historical features of infections due to free-living amebae, its taxonomy and the present nomenclature are briefly reviewed. An analysis of the protozoology of the most frequent agents is done and, based on the author's own experience and the published one, already established anatomo-clinical entities are described: the primary amebic meningoencephalitis, granulomatous amebic encephalitis, Acanthamoeba keratitis, cutaneous acanthamoebiasis, disseminated infection and other rare isolated locations.
自由生活阿米巴引起的感染是最具医学研究价值的新发机会性感染之一。尽管此类感染并不常见,但在世界几乎所有地区均有报道,其诊断依赖于高度的怀疑指数,尤其是在形态病理学和实验室检查中。本文简要回顾了自由生活阿米巴感染令人关注的历史特征、其分类学及当前的命名法。对最常见病原体的原生动物学进行了分析,并根据作者自身经验及已发表的经验,描述了已确立的解剖学临床实体:原发性阿米巴脑膜脑炎、肉芽肿性阿米巴脑炎、棘阿米巴角膜炎、皮肤棘阿米巴病、播散性感染及其他罕见的孤立部位感染。