Miyamoto T, Kambe N, Nishiura S, Mihara M, Shimao S
Department of Dermatology, Tsuyama Central Hospital, Japan.
Dermatologica. 1990;180(1):40-3.
We present a patient with microcystic adnexal carcinoma. The lesion was an indurated plaque on the skin of the right upper lip of a 58-year-old woman which was slowly growing during 27 years. Carcinoembryonic antigen was immunoreactive in the luminal contents of the tumor ducts and in the cytoplasm of cells surrounding ducts. S-100 protein was positive in the cytoplasm of a few cells at the lower dermis. These observations suggested that this tumor was related to sweat glands. Furthermore, electron microscopy revealed that tumor cells had features of eccrine ductal cells. These observations confirm that this tumor appeared at least capable of eccrine duct differentiation.
我们报告一例微囊性附属器癌患者。该病变为一名58岁女性右上唇皮肤的硬结性斑块，在27年中缓慢生长。癌胚抗原在肿瘤导管的管腔内容物及导管周围细胞的细胞质中呈免疫反应阳性。S-100蛋白在真皮下部少数细胞的细胞质中呈阳性。这些观察结果提示该肿瘤与汗腺有关。此外，电子显微镜检查显示肿瘤细胞具有小汗腺导管细胞的特征。这些观察结果证实该肿瘤至少具有小汗腺导管分化能力。
