双环吡唑烷酮的抗菌特性。
Antibacterial properties of the bicyclic pyrazolidinones.
作者信息
Allen N E, Hobbs J N, Preston D A, Turner J R, Wu C Y
机构信息
Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285.
出版信息
J Antibiot (Tokyo). 1990 Jan;43(1):92-9. doi: 10.7164/antibiotics.43.92.
PMID:1689710
Abstract
LY173013 and LY186826 are bicyclic pyrazolidinones containing a novel aza-gamma-lactam ring structure. The antibacterial properties of these compounds appear to be related to those of beta-lactam antibiotics in that both classes of compounds share certain common binding molecules such as beta-lactamases and penicillin-binding proteins.
摘要
LY173013和LY186826是含有新型氮杂-γ-内酰胺环结构的双环吡唑烷酮。这些化合物的抗菌特性似乎与β-内酰胺抗生素的抗菌特性有关，因为这两类化合物都共享某些共同的结合分子，如β-内酰胺酶和青霉素结合蛋白。
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