Goto Hiroshi, Yamamoto Tatsuro, Ishiyama Zenzo, Usui Masahiko, Okada Shinya
Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan.
Department of Pathology, Tokyo Medical University, Tokyo, Japan.
Jpn J Ophthalmol. 2006 Jul-Aug;50(4):374-376. doi: 10.1007/s10384-006-0324-2.
Primary cutaneous adenoid cystic carcinoma is one of the rarest eyelid tumors.
A 39-year-old man presented with a small subcutaneous induration in his left lower eyelid close to the lower lacrimal punctum.
Under a clinical diagnosis of chalazion, the eyelid induration was extracted surgically via the palpebral conjunctiva. Histopathological examination of the extracted tumor revealed proliferation of basaloid cells with a prominent cribriform pattern containing Alcian blue-positive and periodic acid Schiff-positive material, leading to a diagnosis of adenoid cystic carcinoma. The patient subsequently underwent extended radical excision including the lacrimal sac. No recurrence was observed during 20 months after surgery.
Adenoid cystic carcinoma should be considered as a differential diagnosis of eyelid tumors simulating chalazion. Adenoid cystic carcinoma in the eyelid may have a more favorable prognosis than that in the lacrimal gland.
原发性皮肤腺样囊性癌是最罕见的眼睑肿瘤之一。
一名39岁男性患者，其左下眼睑靠近下泪小点处出现一个小的皮下硬结。
临床诊断为睑板腺囊肿，经睑结膜手术切除眼睑硬结。对切除肿瘤的组织病理学检查显示，基底样细胞增生，呈显著的筛状结构，含有阿尔辛蓝阳性和过碘酸希夫阳性物质，诊断为腺样囊性癌。患者随后接受了包括泪囊在内的扩大根治性切除术。术后20个月未观察到复发。
腺样囊性癌应作为模拟睑板腺囊肿的眼睑肿瘤的鉴别诊断。眼睑腺样囊性癌的预后可能比泪腺腺样囊性癌更有利。
