Theall K P, Clark R A, Powell A, Smith H, Kissinger P
School of Public Health and Tropical Medicine, Tulane University Health Sciences Center, New Orleans, LA 70112, USA.
AIDS Behav. 2007 Mar;11(2):205-15. doi: 10.1007/s10461-006-9159-6.
We examine the role of alcohol consumption on sexual risk behavior among a cohort of 187 sexually active HIV-infected women (aged 18-61) in care at an urban ambulatory clinic in New Orleans, Louisiana, U.S. Sexual risk behavior among women on and off antiretroviral therapy (ART) and the relationship between alcohol use, ART, and behavior was also explored. One-fourth of respondents were classified as binge drinkers and the average number of drinking occasions per week ranged from none to 10-12. Approximately 60% were prescribed ART and self-reported adherence was 90%. One-third of the women reported no condom use at last vaginal sex, 62% reported inconsistent condom use for vaginal sex, and 7% had multiple male sex partners in the last month. Binge alcohol users and women on ART were significantly more likely to participate in each sexual risk outcome examined. Partner refusal of condom use was also significantly associated with binge drinking patterns. Results lend strength to the equivocal literature on the relationship between both alcohol and prescription of ART and sexual behavior. Enhanced detection of alcohol abuse, coupled with risk reduction counseling especially among women prescribed ART are important clinical practices in treating women with HIV.
我们在美国路易斯安那州新奥尔良市一家城市门诊诊所接受治疗的187名性活跃的感染艾滋病毒女性（年龄在18 - 61岁之间）队列中，研究了饮酒对性风险行为的影响。同时还探讨了接受和未接受抗逆转录病毒治疗（ART）的女性的性风险行为，以及饮酒、ART与行为之间的关系。四分之一的受访者被归类为酗酒者，每周饮酒次数平均从无到10 - 12次不等。约60%的女性接受了ART治疗，自我报告的依从率为90%。三分之一的女性报告在最后一次阴道性行为时未使用避孕套，62%的女性报告在阴道性行为中避孕套使用不规律，7%的女性在过去一个月中有多个男性性伴侣。酗酒者和接受ART治疗的女性参与所研究的每种性风险行为的可能性显著更高。伴侣拒绝使用避孕套也与酗酒模式显著相关。研究结果为关于酒精与ART处方以及性行为之间关系的不确定文献提供了有力支持。加强对酒精滥用的检测，同时进行风险降低咨询，特别是在接受ART治疗的女性中，是治疗感染艾滋病毒女性的重要临床实践。
