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加纳博戈索黄金有限公司采矿作业区成年居民因接触氰化物而面临的非癌症健康风险评估。

Non-cancer health risk assessment from exposure to cyanide by resident adults from the mining operations of Bogoso Gold Limited in Ghana.

作者信息

Obiri S, Dodoo D K, Okai-Sam F, Essumang D K

机构信息

Environmental Research Group, Department of Chemistry, University of Cape Coast, Cape Coast.

出版信息

Environ Monit Assess. 2006 Jul;118(1-3):51-63. doi: 10.1007/s10661-006-0773-6.

Abstract

Cyanide is a very toxic chemical that is used to extract gold from its ores. Wastewaters from gold mining companies such as Bogoso Gold Limited (BGL) contain cyanide and other potentially toxic chemicals that have adverse effects on human beings and aquatic organisms. This study was conducted to evaluate the human health risk assessment from exposure to free cyanide via oral and dermal contact of surface/underground water by resident adults within the concession of Bogoso Gold Limited. The chronic non-cancer health risk from exposure to cyanide in River Bogo Upstream is 230 and 43 (by Central Tendency Exposure (CTE) parameters respectively). This means that approximately 230 and 43 resident adults are likely to suffer diseases related to cyanide intoxication via oral and dermal contact respectively. For chronic exposure to River Bogo Downstream by resident adults, the non-cancer health risks are: 0.031 and 0.57 via oral and dermal contact for CTE parameters respectively, which also means that, the non-cancer health risks associated with cyanide intoxication is negligible as the hazard index is less than 1.0 via oral and dermal contacts respectively. The results showed that health risk for acute exposure to cyanide by the resident adults is very high. Hence the residents attribute most of the unexplained deaths in the communities to accidental ingestion and dermal contact of cyanide water.

摘要

氰化物是一种剧毒化学品,用于从矿石中提取黄金。来自博戈索黄金有限公司(BGL)等金矿公司的废水含有氰化物和其他潜在有毒化学品,对人类和水生生物有不利影响。本研究旨在评估博戈索黄金有限公司特许区内成年居民通过地表水/地下水的口服和皮肤接触接触游离氰化物对人体健康的风险评估。博戈上游河中氰化物暴露的慢性非癌症健康风险分别为230和43(分别通过中心趋势暴露(CTE)参数)。这意味着,分别约有230名和43名成年居民可能通过口服和皮肤接触患上与氰化物中毒相关的疾病。对于成年居民对博戈下游河的慢性暴露,非癌症健康风险分别为:口服接触为0.031,皮肤接触为0.57(CTE参数),这也意味着,由于口服和皮肤接触的危害指数均小于1.0,与氰化物中毒相关的非癌症健康风险可忽略不计。结果表明,成年居民急性接触氰化物的健康风险非常高。因此,居民将社区中大部分不明原因的死亡归因于氰化物水的意外摄入和皮肤接触。

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