Peck Joshua J, Stout Sam D
Department of Anthropology, The Ohio State University, Columbus, OH 43210-1364, USA.
Am J Phys Anthropol. 2007 Jan;132(1):89-97. doi: 10.1002/ajpa.20464.
For methodological or other reasons, a variety of skeletal elements are analyzed and subsequently used as a basis for describing general bone loss and mass. However, bone loss and mass may not be uniform within and among skeletal elements of the same individual because of biomechanical factors. We test the hypothesis that a homogeneity in bone mass exists among skeletal elements of the same individual. Measures indicative of bone mass were calculated from the midshafts of six skeletal elements from the same individuals (N = 41). The extent of intraskeletal variability in bone mass (relative cortical area) was then examined for the entire sample, according to age, sex, and pathological status. The results of the analysis showed that all measures reflect a heterogeneity in bone mass (P </= 0.001). Specifically, differences were observed between the bones of the upper limb and those of the lower limb. Both sexes showed intraskeletal variability in bone mass, but the difference between the sexes is not significant (P = 0.509). When the sample is subdivided according to age, all groups show intraskeletal variability in bone mass, but the difference did not differ significantly among the groups (P = 0.217). However, significant differences in intraskeletal variability are observed between individuals below and above the age of 50. Pathological individuals show intraskeletal variability in bone mass, but the difference between the pathological and non-pathological groups is not significant (P = 0.095). These results indicate that the bone mass of any particular skeletal element is intricately tethered to its specific mechanical loading environment.
由于方法学或其他原因，人们分析了多种骨骼成分，并随后将其作为描述一般骨质流失和骨量的基础。然而，由于生物力学因素，同一个体的骨骼成分内部和之间的骨质流失和骨量可能并不均匀。我们检验了同一个体的骨骼成分之间存在骨量同质性的假设。从同一批个体（N = 41）的六个骨骼成分的骨干中部计算出指示骨量的指标。然后根据年龄、性别和病理状态，对整个样本中骨骼内部骨量（相对皮质面积）的变异性程度进行了检查。分析结果表明，所有指标都反映了骨量的异质性（P≤0.001）。具体而言，观察到上肢骨骼和下肢骨骼之间存在差异。两性在骨骼内部的骨量都存在变异性，但两性之间的差异不显著（P = 0.509）。当根据年龄对样本进行细分时，所有组在骨骼内部的骨量都存在变异性，但各组之间的差异不显著（P = 0.217）。然而，在50岁以下和50岁以上的个体之间观察到骨骼内部变异性存在显著差异。病理个体在骨骼内部的骨量存在变异性，但病理组和非病理组之间的差异不显著（P = 0.095）。这些结果表明，任何特定骨骼成分的骨量都与其特定的机械负荷环境密切相关。
