[A study on enoxacin concentration in human prostatic tissue].

To examine the penetration of enoxacin into prostatic tissue of patients with benign prostatic hypertropHy, the serum concentration and prostatic tissue level of enoxacin were measured. Enoxacin was administered orally at a dose of 200 mg, three times 2 days and one day before and once on the day of the operation. Blood and prostatic tissue samples were taken during the operation. The mean concentration of enoxacin was 2.84 +/- 0.349 g/ml in serum and 4.60 +/- 0.631 micrograms/ml in the prostatic tissue.