Chang S W, Hou P K, Chen M S
Department of Ophthalmology, National Taiwan University Hospital, Taipei.
Arch Ophthalmol. 1990 Mar;108(3):405-7. doi: 10.1001/archopht.1990.01070050103042.
To elucidate the pathophysiologic features of conjunctival concretions, we performed polarized microscopic examinations, immunocytochemical studies, histochemical stains, and electron microscopic studies of concretions obtained from five patients with chronic conjunctivitis. Electron-dense secretory granules, ranging from 0.2 to 0.5 micron in diameter and stained positively for periodic acid-Schiff and mucicarmine, were found in the superficial lining epithelial cells of the pseudogland of Henle. In view of the granular and membranous figures reflecting degenerating epithelial cells and secretory granules in the concretions, we argue that the concretions, are mostly composed of the mucinous secretion of the transformed conjunctival glands admixed with the degenerative products of the epithelial cells.
为阐明结膜结石的病理生理特征，我们对5例慢性结膜炎患者的结石进行了偏振显微镜检查、免疫细胞化学研究、组织化学染色及电子显微镜研究。在Henle假腺的表层衬里上皮细胞中发现了电子致密的分泌颗粒，直径为0.2至0.5微米，高碘酸-希夫染色和黏液卡红染色呈阳性。鉴于结石中反映变性上皮细胞和分泌颗粒的颗粒状和膜状结构，我们认为结石主要由转化结膜腺的黏液分泌与上皮细胞的退变产物混合而成。
