Paquier Philippe F, De Smet Hyo Jung, Mariën Peter, Poznanski Nathalie, Van Bogaert Patrick
Department of Neurology, Erasme University Hospital ULB, Brussels, Belgium.
J Child Neurol. 2006 Apr;21(4):324-30. doi: 10.1177/08830738060210042101.
The acquired alexia with agraphia syndrome is a conspicuous disorder of reading and writing in the absence of significant other language impairments that has mainly been recorded in adults. Pure cases are rare, with most patients displaying mild aphasic deficits. In children, acquired reading and writing disorders are generally reported as part of more encompassing aphasic syndromes affecting oral and written language equally, for example, Broca or Wernicke aphasia. Documented instances of predominant acquired reading and writing disorders in childhood are exceptional. We report an 11-year-old, right-handed boy who sustained a left temporoparieto-occipital hematoma following rupture of an arteriovenous malformation and who consecutively presented with the acquired alexia with agraphia syndrome associated with word-finding difficulties. Neuropsychologic and neurolinguistic data showed that there was no concomitant Gerstmann and/or angular gyrus syndrome. Th e recoveryfrom the anomia was quite favorable, but recovery of written language was more protracted and acted on the patient's further scholastic achievement. This case is reminiscent of a historical childhood case reported in 1939 and is consonant with adult cases in terms of lesion location and semiologic picture.
获得性失读失写综合征是一种在没有其他明显语言障碍情况下的显著阅读和书写障碍，主要见于成年人。纯病例罕见，大多数患者有轻度失语缺陷。在儿童中，获得性阅读和书写障碍通常作为更广泛的失语综合征的一部分被报道，这些综合征对口语和书面语言的影响相同，例如布罗卡失语或韦尼克失语。有记录的儿童期主要获得性阅读和书写障碍的病例很罕见。我们报告一名11岁右利手男孩，他因动静脉畸形破裂导致左颞顶枕部血肿，随后相继出现获得性失读失写综合征并伴有找词困难。神经心理学和神经语言学数据显示不存在伴随的格斯特曼综合征和/或角回综合征。命名障碍的恢复相当良好，但书面语言的恢复更为持久，并影响了患者的进一步学业成绩。该病例让人想起1939年报道的一例历史上的儿童病例，在病变位置和症状表现方面与成人病例一致。
