Erkiliç Suna, Koçer N Emrah
Department of Pathology, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey.
Acta Cytol. 2006 Jul-Aug;50(4):407-9. doi: 10.1159/000325982.
To evaluate the usefulness of toluidine blue-stained wet films in the preliminary cytologic evaluation of serous effusions by means of specificity, sensitivity, and positive and negative predictive value.
One hundred seventy-six samples consisting of 122 pleural and pericardial effusions and 54 peritoneal effusions from 160 patients were included in the study. A toluidine blue-stained wet film of each sample was evaluated, and diagnoses were compared with the diagnoses by conventional smears and cell blocks on the same sample.
The sensitivity of wet films was 69%, 68% in pleural and pericardial effusions and peritoneal effusions, respectively, and the specificity of wet films was 93%, 92% in pleural and pericardial effusions and peritoneal effusions, respectively. Positive predictive values of smears alone were 78% and 75%; negative predictive values of smears alone were 96% and 95% in pleural and pericardial effusions and peritoneal effusions, respectively.
Preliminary cytologic evaluation of serous effusions with toluidine blue-stained wet films is simple and economical. It provides the opportunity to plan additional procedures for the samples.
通过特异性、敏感性、阳性预测值和阴性预测值，评估甲苯胺蓝染色湿片在浆液性积液初步细胞学评估中的实用性。
本研究纳入了160例患者的176份样本，包括122份胸腔和心包积液以及54份腹腔积液。对每个样本的甲苯胺蓝染色湿片进行评估，并将诊断结果与同一样本的传统涂片和细胞块诊断结果进行比较。
湿片的敏感性分别为69%，胸腔和心包积液及腹腔积液中分别为68%；湿片的特异性分别为93%，胸腔和心包积液及腹腔积液中分别为92%。仅涂片的阳性预测值分别为78%和75%；仅涂片的阴性预测值在胸腔和心包积液及腹腔积液中分别为96%和95%。
用甲苯胺蓝染色湿片对浆液性积液进行初步细胞学评估简单且经济。它为针对样本规划额外的检查程序提供了机会。
