Schifferdecker E
Zentrum der Inneren Medizin, Universität Frankfurt/Main.
Fortschr Med. 1990 Jan 15;108(1):42-4.
An investigation of a large group of patients with Graves' disease demonstrates that this autoimmune disorder of the thyroid is a chronic process with an often protracted course and therefore requires virtually life-long management. Drug therapy (with thionamides) is associated with a high rate of relapse of 60-70%-reliable criteria for the cessation of the autoimmune process are not available. Surgical therapy may also fail to provide lasting control of hyperthyroidism.
对一大群格雷夫斯病患者的调查表明，这种甲状腺自身免疫性疾病是一个慢性过程，病程往往迁延，因此实际上需要终身管理。药物治疗（使用硫代酰胺）的复发率很高，为60%-70%，目前尚无确定自身免疫过程停止的可靠标准。手术治疗也可能无法持久控制甲亢。
