Aceti A, Celestino D, Caferro M, Teggi A, Pennica A, Adriani E, Grilli A, Paparo S, Leri O, De Rosa F
Istituto di Clinica delle Malattie Tropicali e Infettive, Università La Sapienza, Roma, Italia.
Int Arch Allergy Appl Immunol. 1990;91(1):111-2. doi: 10.1159/000235099.
We studied immunoglobulin E (IgE)- and non-IgE-mediated releasability in basophils from 31 patients with hydatidosis. Histamine release to non-IgE-dependent stimuli did not differ significantly between normal individuals and patients with hydatidosis. On the contrary, an increased histamine liberation was obtained by challenging basophils from hydatid patients with anti-human IgE. It is concluded that Echinococcus granulosus infection induces an enhanced sensitivity of basophils to IgE-dependent stimuli.
