Gust R, Kleine P, Fabel H
Abteilung für Pneumologie der Medizinischen Hochschule Hannover.
Med Klin (Munich). 1990 Jan 15;85(1):18-23.
In a prospective randomized study the effect of pleurodesis using fibrin-glue was compared with pleurodesis using tetracycline in the management of malignant pleural effusions. Intrapleural therapy with fibrin-glue was significantly more effective concerning long-term results as relapse of pleural effusion and improvement of lung function just as time of draining pleural effusion and pain during the application of fibrin glue/tetracycline. Thus, intracavitary therapy with fibrin glue may be recommended in the control of malignant pleural effusions.
