Horváth T, Orosz E, Czenkár B
Orv Hetil. 1989 May 14;130(20):1051-2.
Eleven patients were treated with chest tube drainage and intrapleural instillation of tetracycline for malignant pleural effusion. In ten cases this procedure for 6-10 days achieved complete resolution of pleural fluid and produced pleurodesis. Only one patient needed longer treatment, but it was also successful. Fluid recurrence was not recognised during the follow-up period. This method is very effective and simple, so the authors recommend the tetracycline pleurodesis for the palliative management of malignant pleural effusions.
11例恶性胸腔积液患者接受了胸腔闭式引流及胸腔内注入四环素治疗。10例患者经此方法治疗6 - 10天后胸腔积液完全消退并产生胸膜固定术。仅1例患者需要更长时间的治疗，但也获得成功。随访期间未发现积液复发。该方法非常有效且简单，因此作者推荐四环素胸膜固定术用于恶性胸腔积液的姑息治疗。
