Malik Tahir Qayyum, Joseph Y T, Ghacha Reda, Abdelrahman Mohammed, Karkar Ayman
Department of Nephrology, Dammam Central Hospital, Kanoo Kidney Center, Saudi Arabia.
Saudi J Kidney Dis Transpl. 2006 Jun;17(2):200-2.
We report a 19-year-old Saudi female with nephrotic syndrome whose renal biopsy revealed findings suggestive of minimal change glomerulonephritis (MCGN). She developed oliguric renal failure requiring hemodialysis. She remained dialysis dependent for five weeks and subsequently renal function recovered fully. She remained nephrotic and responded to a six week course of corticosteroids. She was followed for two years during which she had two relapses, which responded to steroids. Acute renal failure is uncommon in MCGN and is due to acute tubular necrosis induced by hypovolemia or drugs. This patient did not have any obvious precipitating factor, which led to acute reversible renal failure.
我们报告了一名19岁的沙特女性肾病综合征患者,其肾活检结果提示为微小病变性肾小球肾炎(MCGN)。她发展为少尿性肾衰竭,需要进行血液透析。她持续依赖透析五周,随后肾功能完全恢复。她仍为肾病状态,对为期六周的皮质类固醇疗程有反应。对她进行了两年的随访,期间她有两次复发,均对类固醇有反应。急性肾衰竭在MCGN中并不常见,是由血容量不足或药物引起的急性肾小管坏死所致。该患者没有任何明显的诱发因素却导致了急性可逆性肾衰竭。