Rincon Leonor Garcia, Rocha Manoel Otávio da Costa, Pires Marco Túlio Baccarini, Oliveira Bruna Guimarães, Barros Vladimir da Costa Val, Barros Marcio Vinicius Lins, Ribeiro Antônio Luiz Pinho
Pós-Graduação em Ciências da Saúde, Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, R. Campanha 98/101, 30310-770 Belo Horizonte, MG, Brazil.
Rev Soc Bras Med Trop. 2006 May-Jun;39(3):245-9. doi: 10.1590/s0037-86822006000300003.
The aim of this study was to compare Chagas and non-Chagas' disease patients using single or dual-chamber pacemaker in relation to the ejection fraction of the left ventricle, the ventricular stimulation threshold and the occurrence of ventricular arrhythmia. From January, 2001 to November, 2002, 45 Chagas' disease patients and 35 non-Chagas' disease patients, all pacemaker users, were evaluated considering clinical history, echocardiographic study, Holter monitoring and analysis of the pacemaker telemetry data. Chagas' disease patients were significantly younger, but both groups were similar when chest X-Ray variables and right ventricular stimulation threshold were analyzed. Chagas' disease patients had a lower left ventricular ejection fraction and more frequent ventricular arrhythmia during Holter monitoring. A positive correlation between the low ejection fraction of the left ventricle and the intensity of ventricular arrhythmia was observed. In conclusion, among pacemaker user patients, Chagas' disease is related to cardiac markers of worse prognosis.
本研究的目的是比较使用单腔或双腔起搏器的恰加斯病患者和非恰加斯病患者在左心室射血分数、心室刺激阈值及室性心律失常发生情况方面的差异。2001年1月至2002年11月，对45例恰加斯病患者和35例非恰加斯病患者（均为起搏器使用者）进行了评估，评估内容包括临床病史、超声心动图检查、动态心电图监测以及起搏器遥测数据分析。恰加斯病患者明显更年轻，但在分析胸部X线变量和右心室刺激阈值时，两组相似。恰加斯病患者左心室射血分数较低，且在动态心电图监测期间室性心律失常更频繁。观察到左心室射血分数低与室性心律失常强度之间呈正相关。总之，在起搏器使用者患者中，恰加斯病与预后较差的心脏标志物有关。
