[急性运动对久坐男性餐后血脂异常的影响]

[Effects of acute exercise on postprandial lipemia in sedentary men].

作者信息

Teixeira Mônica, Kasinski Nelson, Izar Maria Cristina de Oliveira, Barbosa Luiz Alberto, Novazzi José Paulo, Pinto Leonor Almeida, Tufik Sérgio, Leite Turíbio Ferreira, Fonseca Francisco Antonio Helfenstein

机构信息

Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP.

出版信息

Arq Bras Cardiol. 2006 Jul;87(1):3-11. doi: 10.1590/s0066-782x2006001400002.

DOI:10.1590/s0066-782x2006001400002

PMID:16906264

Abstract

OBJECTIVE

To examine the effects of a single session of isometric physical exercise on postprandial triglyceridemia in sedentary male individuals with fasting triglycerides values < 150 mg/dl (NTG) or > " 150 mg/dl (TG ALT).

METHODS

Twenty-seven individuals (10 NTG and 17 TG ALT), aged between 30-55 years were assessed in the study. Triglycerides were determined in the beginning, and at two, four and six hours after the oral ingestion of a solution with 50 g/m2 of fat in two occasions: at rest and after treadmill isometric exercise.

RESULTS

Acute exercise did not affect the levels of postprandial triglycerides or the area under the curve (AUC) of triglycerides. However, the abnormal pattern of postprandial lipemia curve was associated with higher basal triglyceridemia with exercise (basal TG: 147 +/- 90 vs. 238 +/- 89 mg/dl, p = 0.02) and without exercise (basal TG: 168 +/- 93 vs. 265 +/- 140 mg/dl, p = 0.04). Analysis of the receiver operating characteristics (ROC) curves showed cut-off values for basal triglycerides with exercise of 166.5 mg/dl (sensitivity: 0.78; specificity: 0.72) and AUC of 0.772 [CI 95%: 0.588-0.955], and without exercise of 172 mg/dl (sensitivity: 0.78; specificity: 0.61) and AUC: 0.722 [CI 95%: 0.530-0.914].

CONCLUSION

Acute exercise did not affect postprandial triglyceridemia in sedentary male individuals, and basal triglyceride levels are predictors of an abnormal response of postprandial triglycerides.

摘要

目的

研究单次等长体育锻炼对空腹甘油三酯值<150mg/dl（正常甘油三酯组，NTG）或>150mg/dl（高甘油三酯组，TG ALT）的久坐男性餐后甘油三酯血症的影响。

方法

本研究评估了27名年龄在30 - 55岁之间的个体（10名NTG和17名TG ALT）。在两种情况下测定甘油三酯水平：一次是在静息状态下，另一次是在跑步机等长运动后，分别在口服含50g/m²脂肪的溶液后的开始阶段、两小时、四小时和六小时进行测定。

结果

急性运动并未影响餐后甘油三酯水平或甘油三酯曲线下面积（AUC）。然而，餐后血脂曲线的异常模式与运动时较高的基础甘油三酯血症相关（基础甘油三酯：运动时147±90 vs. 238±89mg/dl，p = 0.02）以及不运动时相关（基础甘油三酯：不运动时168±93 vs. 265±140mg/dl，p = 0.04）。受试者工作特征（ROC）曲线分析显示，运动时基础甘油三酯的截断值为166.5mg/dl（敏感性：0.78；特异性：0.72），AUC为0.772 [95%置信区间：0.588 - 0.955]，不运动时基础甘油三酯的截断值为172mg/dl（敏感性：0.78；特异性：0.61），AUC为0.722 [95%置信区间：0.530 - 0.914]。