Wu Eric Q, Shi Lizheng, Birnbaum Howard, Hudson Teresa, Kessler Ronald
Analysis Group, Inc., Boston, MA 02199, USA.
Psychol Med. 2006 Nov;36(11):1535-40. doi: 10.1017/S0033291706008191. Epub 2006 Aug 15.
Schizophrenia is a debilitating chronic mental illness. However, the annual prevalence of schizophrenia is not well understood because of under-representation of schizophrenia patients in epidemiological surveys. This study used multiple administrative claims databases to estimate the annual prevalence of diagnosed schizophrenia in the USA.
The annual prevalence of diagnosed schizophrenia in the USA was estimated for different health insurance coverage groups. The prevalence for privately insured individuals was calculated from an administrative claims database of approximately 3 million privately insured beneficiaries covering the period 1999-2003. The prevalence for Medicaid enrollees was calculated from California Medicaid claims covering the period 2000-2002. The prevalence for Medicare and Medicaid/Medicare dual eligibles was estimated using a combination of both databases. Published statistics were used to estimate the prevalence of schizophrenia in the uninsured and veteran populations and to weight the prevalence rates obtained to the population of the USA.
The 12-month prevalence of diagnosed schizophrenia in the USA in 2002 was estimated at 5.1 per 1000 lives. The Medicaid population was identified with the highest prevalence rate among the populations studied. Sensitivity analyses taking into consideration the Veterans Affairs population only changed the estimate slightly to 5.3 per 1000 lives.
Analyses of administrative claims data contribute to the understanding of the prevalence of diagnosed schizophrenia.
精神分裂症是一种使人衰弱的慢性精神疾病。然而，由于精神分裂症患者在流行病学调查中的代表性不足，其年患病率尚未得到很好的了解。本研究使用多个行政索赔数据库来估计美国确诊精神分裂症的年患病率。
针对不同医疗保险覆盖组估计美国确诊精神分裂症的年患病率。通过一个涵盖1999 - 2003年期间约300万私人保险受益人的行政索赔数据库计算私人保险个体的患病率。通过涵盖2000 - 2002年期间的加利福尼亚医疗补助索赔计算医疗补助参保者的患病率。医疗保险和医疗补助/医疗保险双重资格者的患病率使用两个数据库的组合进行估计。已发表的统计数据用于估计未参保人群和退伍军人人群中精神分裂症的患病率，并将获得的患病率加权至美国人口。
2002年美国确诊精神分裂症的12个月患病率估计为每1000人中有5.1人。在所研究的人群中，医疗补助人群的患病率最高。仅考虑退伍军人事务人群的敏感性分析仅将估计值略微改变为每1000人中有5.3人。
行政索赔数据分析有助于了解确诊精神分裂症的患病率。
