Davis Mark D P, Weenig Roger H, Genebriera Joseph, Wendelschafer-Crabb Gwen, Kennedy William R, Sandroni Paola
Department of Dermatology, Mayo Clinic, Rochester, MN 55905, USA.
J Am Acad Dermatol. 2006 Sep;55(3):519-22. doi: 10.1016/j.jaad.2006.04.067.
The histopathology of primary erythromelalgia has been poorly characterized. A total of 33 skin biopsy specimens from 29 patients with a diagnosis of primary erythromelalgia were re-examined. Histopathologic findings were nonspecific. Vascular thrombi were not identified. A relative decrease in small nerve fiber density was noted in specimens from 13 of 16 patients.
原发性红斑性肢痛症的组织病理学特征尚不明确。对29例诊断为原发性红斑性肢痛症患者的33份皮肤活检标本进行了重新检查。组织病理学结果无特异性。未发现血管血栓。在16例患者中的13例标本中发现小神经纤维密度相对降低。