内皮衍生的一氧化氮在细胞因子诱导的低血压中起作用吗？ - Suppr

Does endothelium-derived nitric oxide have a role in cytokine-induced hypotension?

作者信息

Nathan C F, Stuehr D J

机构信息

Beatrice and Samuel A. Seaver Laboratory, Department of Medicine, Cornell University Medical School, New York, NY 10021.

出版信息

J Natl Cancer Inst. 1990 May 2;82(9):726-8. doi: 10.1093/jnci/82.9.726.

DOI:10.1093/jnci/82.9.726

PMID:1691302

Abstract

摘要

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Does endothelium-derived nitric oxide have a role in cytokine-induced hypotension?内皮衍生的一氧化氮在细胞因子诱导的低血压中起作用吗？

J Natl Cancer Inst. 1990 May 2;82(9):726-8. doi: 10.1093/jnci/82.9.726.

Therapeutic Antibody-Induced Vascular Toxicity Due to Off-Target Activation of Nitric Oxide in Cynomolgus Monkeys.食蟹猴中因一氧化氮脱靶激活导致的治疗性抗体诱导的血管毒性

Toxicol Sci. 2016 Jun;151(2):245-60. doi: 10.1093/toxsci/kfw037. Epub 2016 Feb 25.

What is the relationship between the endothelium derived relaxant factor and nitric oxide?内皮源性舒张因子与一氧化氮之间有什么关系？

Life Sci. 1989;45(1):1-14. doi: 10.1016/0024-3205(89)90429-3.

Atorvastatin restores the impaired vascular endothelium-dependent relaxations mediated by nitric oxide and endothelium-derived hyperpolarizing factors but not hypotension in sepsis.阿托伐他汀恢复了脓毒症中由一氧化氮和内皮衍生超极化因子介导的受损血管内皮依赖性舒张作用，但不降低血压。

J Cardiovasc Pharmacol. 2009 Dec;54(6):526-34. doi: 10.1097/FJC.0b013e3181bfafd6.

Endothelial cell production of nitrogen oxides in response to interferon gamma in combination with tumor necrosis factor, interleukin-1, or endotoxin.内皮细胞在干扰素γ与肿瘤坏死因子、白细胞介素-1或内毒素联合作用下产生氮氧化物。

J Natl Cancer Inst. 1990 May 2;82(9):772-6. doi: 10.1093/jnci/82.9.772.

EDHF-mediated rapid restoration of hypotensive response to acetylcholine after chronic, but not acute, nitric oxide synthase inhibition in rats.在大鼠中，慢性而非急性抑制一氧化氮合酶后，内皮衍生超极化因子介导的对乙酰胆碱的降压反应快速恢复。

Eur J Pharmacol. 2006 Sep 28;546(1-3):120-6. doi: 10.1016/j.ejphar.2006.06.072. Epub 2006 Jul 5.

Effect of 1-week treatment with erythropoietin on the vascular endothelial function in anaesthetized rabbits.促红细胞生成素一周治疗对麻醉兔血管内皮功能的影响。

Br J Pharmacol. 2001 Jun;133(3):395-405. doi: 10.1038/sj.bjp.0704083.

Role of nitric oxide production in anaphylaxis and its relevance for the treatment of anaphylactic hypotension with methylene blue.一氧化氮生成在过敏反应中的作用及其与亚甲蓝治疗过敏性低血压的相关性。

Ann Allergy Asthma Immunol. 2007 Oct;99(4):306-13. doi: 10.1016/S1081-1206(10)60545-5.

Disruption of Physiological Balance Between Nitric Oxide and Endothelium-Dependent Hyperpolarization Impairs Cardiovascular Homeostasis in Mice.一氧化氮与内皮依赖性超极化之间生理平衡的破坏损害小鼠心血管稳态。

Arterioscler Thromb Vasc Biol. 2016 Jan;36(1):97-107. doi: 10.1161/ATVBAHA.115.306499. Epub 2015 Nov 5.

Essential role of nitric oxide in sepsis-induced impairment of endothelium-derived hyperpolarizing factor-mediated relaxation in rat pulmonary artery.一氧化氮在脓毒症引起的大鼠肺动脉内皮源性超极化因子介导的松弛功能障碍中的重要作用。

Eur J Pharmacol. 2010 Mar 25;630(1-3):84-91. doi: 10.1016/j.ejphar.2009.12.026. Epub 2009 Dec 24.

引用本文的文献

Intragastric nicotine protects against 40% ethanol-induced gastric injury despite pretreatment with NG-nitro-L-arginine methyl ester or adrenal medullectomy in rats.尽管对大鼠预先给予NG-硝基-L-精氨酸甲酯或进行肾上腺髓质切除术，胃内尼古丁仍可预防40%乙醇诱导的胃损伤。

Dig Dis Sci. 1994 Feb;39(2):347-52. doi: 10.1007/BF02090207.

Regulation of staphylococcal enterotoxin B-elicited nitric oxide production by endothelial cells.内皮细胞对葡萄球菌肠毒素B诱导的一氧化氮产生的调节作用

Infect Immun. 1995 Feb;63(2):539-46. doi: 10.1128/iai.63.2.539-546.1995.

Tumor necrosis factor alpha activates soluble guanylate cyclase in bovine glomerular mesangial cells via an L-arginine-dependent mechanism.肿瘤坏死因子α通过一种依赖L-精氨酸的机制激活牛肾小球系膜细胞中的可溶性鸟苷酸环化酶。

J Exp Med. 1990 Dec 1;172(6):1843-52. doi: 10.1084/jem.172.6.1843.

Inhibition of the release of endothelium-derived relaxing factor in vitro and in vivo by dipeptides containing NG-nitro-L-arginine.含NG-硝基-L-精氨酸的二肽对体外和体内内皮源性舒张因子释放的抑制作用。

Br J Pharmacol. 1991 Sep;104(1):31-8. doi: 10.1111/j.1476-5381.1991.tb12380.x.

Purification of a soluble isoform of guanylyl cyclase-activating-factor synthase.鸟苷酸环化酶激活因子合酶可溶性同工型的纯化。

Proc Natl Acad Sci U S A. 1991 Jan 15;88(2):365-9. doi: 10.1073/pnas.88.2.365.

N-hydroxylamine is not an intermediate in the conversion of L-arginine to an activator of soluble guanylate cyclase in neuroblastoma N1E-115 cells.在神经母细胞瘤N1E-115细胞中，N-羟胺不是L-精氨酸转化为可溶性鸟苷酸环化酶激活剂过程中的中间体。

Biochem J. 1991 Feb 1;273 ( Pt 3)(Pt 3):547-52. doi: 10.1042/bj2730547.

Interleukin 1 induces prolonged L-arginine-dependent cyclic guanosine monophosphate and nitrite production in rat vascular smooth muscle cells.白细胞介素1诱导大鼠血管平滑肌细胞中依赖L-精氨酸的环磷酸鸟苷和亚硝酸盐产生延长。

J Clin Invest. 1991 Feb;87(2):602-8. doi: 10.1172/JCI115036.

Activated macrophages depress the contractility of rabbit carotids via an L-arginine/nitric oxide-dependent effector mechanism. Connection with amplified cytokine release.活化的巨噬细胞通过一种依赖L-精氨酸/一氧化氮的效应机制降低兔颈动脉的收缩性。与细胞因子释放增加有关。

J Clin Invest. 1992 Mar;89(3):851-60. doi: 10.1172/JCI115664.

Feedback suppression of staphylococcal enterotoxin-stimulated T-lymphocyte proliferation by macrophages through inductive nitric oxide synthesis.巨噬细胞通过诱导型一氧化氮合成对葡萄球菌肠毒素刺激的T淋巴细胞增殖的反馈抑制。

Infect Immun. 1992 Nov;60(11):4832-7. doi: 10.1128/iai.60.11.4832-4837.1992.

N omega-amino-L-arginine, an inhibitor of nitric oxide synthase, raises vascular resistance but increases mortality rates in awake canines challenged with endotoxin.Nω-氨基-L-精氨酸，一种一氧化氮合酶抑制剂，可提高血管阻力，但会增加清醒犬对内毒素刺激的死亡率。

J Exp Med. 1992 Oct 1;176(4):1175-82. doi: 10.1084/jem.176.4.1175.

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Does endothelium-derived nitric oxide have a role in cytokine-induced hypotension?

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