胎牛血清会改变环磷酸腺苷在体外对血红素合成的影响。
Fetal calf serum alters cyclic adenosine 3',5'-monophosphate's effect on heme synthesis in vitro.
作者信息
Olander C P
出版信息
Experientia. 1975 Aug 15;31(8):981-3. doi: 10.1007/BF02358890.
PMID:169145
Abstract
An investigation of the effect of cAMP on heme synthesis of rat bone marrow cells revealed that at 10(-2) M this cyclic nucleotide inhibits heme synthesis and that optimum stimulation occurs at 10(-4) M. Some unidentified constituent of fetal calf serum in the culture medium modifies the direction and degree of cAMP's effect.
摘要
一项关于环磷酸腺苷（cAMP）对大鼠骨髓细胞血红素合成影响的研究表明，在10⁻² M浓度时，这种环核苷酸会抑制血红素合成，而在10⁻⁴ M浓度时会出现最佳刺激效果。培养基中胎牛血清的某些未明确成分会改变cAMP作用的方向和程度。
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