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Detergent extraction of the human alpha-beta interferon receptor: a soluble form capable of binding interferon.

作者信息

Eid P, Mogensen K

机构信息

Laboratory of Viral Oncology (UPR 274/CNRS), Villejuif, France.

出版信息

Biochim Biophys Acta. 1990 Apr 23;1034(1):114-7. doi: 10.1016/0304-4165(90)90161-o.

Abstract

After examining a variety of detergents we find that receptors for human alpha interferon can be solubilized, in active form, from plasma membranes of lymphoid cells using the detergent CHAPS. The complexes formed, in solution, with interferon are stable enough to be separated chromatographically.

摘要

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