模式生物中的Myc：来自果蝇研究室的观点。
Myc in model organisms: a view from the flyroom.
作者信息
de la Cova Claire, Johnston Laura A
机构信息
Department of Genetics & Development, Columbia University Medical Center, New York, NY 10032, USA.
出版信息
Semin Cancer Biol. 2006 Aug;16(4):303-12. doi: 10.1016/j.semcancer.2006.07.010. Epub 2006 Jul 14.
Abstract
The Myc transcription factor regulates fundamental processes in a cell's life: its growth, division, and survival. Myc is conserved throughout metazoan phyla, and its identification in the fruit fly, Drosophila melanogaster has led to new insights in Myc's physiological roles. In this review, we describe recent research on the biology of Myc and its family members in Drosophila, paying particular attention to its role in the control of growth during development.
摘要
Myc转录因子调控细胞生命中的基本过程：其生长、分裂和存活。Myc在整个后生动物门中都保守存在，它在果蝇（黑腹果蝇）中的发现为Myc的生理作用带来了新的见解。在这篇综述中，我们描述了果蝇中Myc及其家族成员生物学的最新研究，特别关注其在发育过程中生长控制方面的作用。
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