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Structural and functional features of the HIV envelope glycoprotein and considerations for vaccine development.

作者信息

Putney S D, Rusche J, Javaherian K, Matthews T, Bolognesi D

出版信息

Biotechnology. 1990;14:81-110. doi: 10.1016/b978-0-409-90116-0.50013-3.

DOI:10.1016/b978-0-409-90116-0.50013-3
PMID:1691670
Abstract
摘要

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J Virol. 1992 Apr;66(4):2547-50. doi: 10.1128/JVI.66.4.2547-2550.1992.
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Human immunodeficiency virus type 1 envelope glycoprotein molecules containing membrane fusion-impairing mutations in the V3 region efficiently undergo soluble CD4-stimulated gp120 release.1型人类免疫缺陷病毒包膜糖蛋白分子在V3区域含有损害膜融合的突变,可有效进行可溶性CD4刺激的gp120释放。
J Virol. 1992 Oct;66(10):6208-12. doi: 10.1128/JVI.66.10.6208-6212.1992.