Terada Y, Ino T, Wanibuchi Y, Takagi H, Shimoyama Y, Furuta S
Department of Cardiovascular Surgery, Mitsui Memorial Hospital, Tokyo, Japan.
Nihon Kyobu Geka Gakkai Zasshi. 1990 Jan;38(1):150-3.
This is a report of the management of a patient with chronic idiopathic thrombocytopenic purpura (ITP) and ischemic heart disease. High-dose transvenous gamma-globulin therapy (400 mg/kg/day for five days) was started five days prior to operation, yielding an increase in platelet count from 5.8 X 10(4)/mm3 to 12.8 X 10(4)/mm3. Platelet transfusion was used at the end of cardiopulmonary bypass and on the first postoperative day. There were no problems with hemostasis during the operative procedure and the postoperative course was uneventful. We prefer high-dose transvenous gamma-globulin therapy for ITP prior to open heart surgery as a treatment of choice.
这是一篇关于一名患有慢性特发性血小板减少性紫癜(ITP)和缺血性心脏病患者的治疗报告。在手术前五天开始进行大剂量静脉注射丙种球蛋白治疗(400mg/kg/天,持续五天),血小板计数从5.8×10⁴/mm³增加至12.8×10⁴/mm³。在体外循环结束时和术后第一天使用了血小板输注。手术过程中止血没有问题,术后过程平稳。我们更倾向于在心脏直视手术前对ITP采用大剂量静脉注射丙种球蛋白治疗作为首选治疗方法。