来自巴西圣保罗州的一个样本群体的基因组血统。
Genomic ancestry of a sample population from the state of São Paulo, Brazil.
作者信息
Ferreira Luzitano Brandão, Mendes-Junior Celso Teixeira, Wiezel Cláudia Emília Vieira, Luizon Marcelo Rizzatti, Simões Aguinaldo Luiz
机构信息
Departamento de Genética, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, 14049-900 Ribeirão Preto, São Paulo, Brazil.
出版信息
Am J Hum Biol. 2006 Sep-Oct;18(5):702-5. doi: 10.1002/ajhb.20474.
Allelic frequencies of eight autosomal short-tandem repeat (STR) loci (TH01, TPOx, CSF1PO, vWA, FES/FPS, F13A1, F13B, and CD4) were determined in 400 individuals born in the State of São Paulo. No significant deviations from Hardy-Weinberg equilibrium were found in any loci analyzed. The Unweighted Pair-Group Method with Arithmetic Mean (UPGMA) tree constructed based on genetic distances revealed that the present population was grouped with Europeans, and separated from African and Amerindian populations. Estimates of admixture components based on the gene identity method revealed 79% European, 14% African, and 7% Amerindian contributions to this Brazilian population sample.
在400名出生于圣保罗州的个体中，测定了8个常染色体短串联重复序列（STR）位点（TH01、TPOx、CSF1PO、vWA、FES/FPS、F13A1、F13B和CD4）的等位基因频率。在所分析的任何位点中，均未发现与哈迪-温伯格平衡有显著偏差。基于遗传距离构建的算术平均非加权配对组方法（UPGMA）树显示，当前人群与欧洲人群归为一组，与非洲和美洲印第安人群体分开。基于基因同一性方法的混合成分估计显示，该巴西人群样本中有79%的欧洲人贡献、14%的非洲人贡献和7%的美洲印第安人贡献。
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