Akin Oguz, Schwartz Lawrence H, Welber Adam, Maier Cynthia F, Decorato Douglas R, Panicek David M
Department of Radiology, Memorial SloanKettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.
Clin Imaging. 2006 Sep-Oct;30(5):322-5. doi: 10.1016/j.clinimag.2006.02.006.
To compare breath-hold fast-recovery fast spin echo (FR-FSE) and non-breath-hold fast spin echo (FSE) T2-weighted sequences for hepatic lesion conspicuity and image quality at MR imaging.
Fifty-nine patients with known or suspected liver lesions underwent hepatic MR imaging by using a breath-hold FR-FSE T2-weighted sequence with and without fat suppression and a non-breath-hold FSE T2-weighted sequence with and without fat suppression. Quantitative analysis was made with measurements of the signal intensity of the liver, spleen, background noise, and up to three liver lesions, as well as calculations of the liver signal-to-noise ratio (SNR) and the liver-to-lesion contrast-to-noise ratio (CNR) for each sequence. Qualitative analysis was made for image quality and the number of lesions identified. Statistical analysis was performed by using a single-tailed paired Student's t test with a 95% confidence interval.
SNR and CNR were significantly higher (P<.05) for FSE with fat suppression than for FR-FSE with fat suppression. No statistically significant difference was seen in terms of SNR and CNR between non-fat-suppressed FSE and FR-FSE sequences. Lesion conspicuity, liver edge sharpness, and clarity of vessels were superior and ghosting was less with the FR-FSE sequences compared with the FSE sequences.
Breath-hold FR-FSE technique is a reasonable alternative in T2-weighted imaging of the liver.
比较屏气快速恢复快速自旋回波（FR-FSE）和非屏气快速自旋回波（FSE）T2加权序列在肝脏病变显示及磁共振成像图像质量方面的表现。
59例已知或疑似肝脏病变的患者接受肝脏磁共振成像检查，检查采用了屏气FR-FSE T2加权序列（有无脂肪抑制）和非屏气FSE T2加权序列（有无脂肪抑制）。进行定量分析时，测量肝脏、脾脏、背景噪声以及多达三个肝脏病变的信号强度，并计算每个序列的肝脏信噪比（SNR）和肝脏与病变的对比噪声比（CNR）。对图像质量和识别出的病变数量进行定性分析。采用单尾配对学生t检验及95%置信区间进行统计分析。
脂肪抑制的FSE序列的SNR和CNR显著高于脂肪抑制的FR-FSE序列（P<0.05）。非脂肪抑制的FSE和FR-FSE序列在SNR和CNR方面无统计学显著差异。与FSE序列相比，FR-FSE序列在病变显示、肝脏边缘清晰度和血管清晰度方面更优，且伪影更少。
屏气FR-FSE技术是肝脏T2加权成像的合理替代方法。
