Perseius Kent-Inge, Andersson Eva, Asberg Marie, Samuelsson Mats
Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Scand J Caring Sci. 2006 Sep;20(3):302-7. doi: 10.1111/j.1471-6712.2006.00408.x.
The aims of the study were to: (i) test the reliability of a health-related quality of life (HRQOL) instrument [Swedish Health-Related Quality of Life Survey (SWED-QUAL)] on women patients with borderline personality disorder (BPD); (ii) compare their HRQOL to a normal population group comparable in age; and (iii) test for subgroup differences in HRQOL considering psychiatric DSM axis-I comorbidity.
The study was conducted in connection to a randomized, controlled trial of psychotherapy for women BPD patients. Seventy-five women with BPD diagnosis were administered the SWED-QUAL. Statistic reliability was evaluated with inter-item correlations, total-item correlations and internal consistency criterions. The BPD patients' SWED-QUAL results were compared with data extracted from a published study and subgroup differences due to axis-I comorbidity were analysed.
SWED-QUAL could be considered as an instrument with acceptable reliability when assessing HRQOL in BPD patients. The BPD patients suffered significant impairments in HRQOL overall health dimensions compared to normal population. There were no subgroup differences due to axis-I comorbidity, which indicate that BPD in itself might be a predictor of substantial HRQOL impairment.
本研究的目的是：（i）测试一种与健康相关的生活质量（HRQOL）工具[瑞典健康相关生活质量调查（SWED-QUAL）]在边缘型人格障碍（BPD）女性患者中的可靠性；（ii）将她们的HRQOL与年龄匹配的正常人群组进行比较；以及（iii）考虑精神疾病诊断与统计手册（DSM）轴I共病情况，测试HRQOL的亚组差异。
本研究与一项针对BPD女性患者的心理治疗随机对照试验相关。75名被诊断为BPD的女性接受了SWED-QUAL测试。通过项目间相关性、总项目相关性和内部一致性标准评估统计可靠性。将BPD患者的SWED-QUAL结果与从一项已发表研究中提取的数据进行比较，并分析因轴I共病导致的亚组差异。
在评估BPD患者的HRQOL时，SWED-QUAL可被视为一种具有可接受可靠性的工具。与正常人群相比，BPD患者在HRQOL的总体健康维度上存在显著损害。因轴I共病未出现亚组差异，这表明BPD本身可能是HRQOL严重损害的一个预测因素。
