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一种治疗结肠血管发育异常的新方法。

A novel method of treating colonic angiodysplasia.

作者信息

Suzuki Noriko, Arebi Naila, Saunders Brian P

机构信息

Wolfson Unit for Endoscopy, St Mark's Hospital, Harrow, Middlesex, United Kingdom.

出版信息

Gastrointest Endosc. 2006 Sep;64(3):424-7. doi: 10.1016/j.gie.2006.04.032.

Abstract

BACKGROUND

Colonic angiodysplasia is responsible for up to a third of lower-GI bleeding cases. Argon plasma coagulation (APC) is a recognized treatment modality, but active bleeding decreases the ablative efficacy of APC by dissipation of the energy. APC has been associated with colonic perforation.

OBJECTIVES

We propose a novel and safe method for the treatment of colonic angiodysplasia by a submucosal injection of a saline epinephrine solution followed by the application of APC.

PATIENTS

Three patients with a total of 10 colonic angiodysplasias were treated with this injection-APC method.

INTERVENTIONS

Saline adrenaline solution (1:200,000) 2 to 3 mL was injected beneath the angiodysplasia before application of APC. APC 50 W and gas flow 2 L were applied onto the vascular lesion until the sufficient thermal effect was observed.

RESULTS

There were no procedure-related complications.

CONCLUSIONS

This new injection-APC method was safe for the treatment of colonic angiodysplasia. This may be useful in treating right-sided colonic lesions where the risks of perforation are greater than for the rest of the colon.

摘要

背景

结肠血管发育异常是导致高达三分之一的下消化道出血病例的原因。氩等离子体凝固术(APC)是一种公认的治疗方式,但活动性出血会因能量消散而降低APC的消融效果。APC与结肠穿孔有关。

目的

我们提出一种通过黏膜下注射盐水肾上腺素溶液然后应用APC来治疗结肠血管发育异常的新颖且安全的方法。

患者

3例患者共10处结肠血管发育异常接受了这种注射-APC方法治疗。

干预措施

在应用APC之前,将2至3毫升盐水肾上腺素溶液(1:200,000)注射到血管发育异常下方。将50瓦的APC和2升的气流应用于血管病变部位,直到观察到足够的热效应。

结果

未出现与手术相关的并发症。

结论

这种新的注射-APC方法治疗结肠血管发育异常是安全的。这可能有助于治疗右侧结肠病变,因为此处穿孔风险高于结肠其他部位。

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