在枯草芽孢杆菌中，ScoC和SinR通过共抑制作用对epr进行负调控。
ScoC and SinR negatively regulate epr by corepression in Bacillus subtilis.
作者信息
Kodgire Prashant, Dixit Madhulika, Rao K Krishnamurthy
机构信息
School of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai 400076, India.
出版信息
J Bacteriol. 2006 Sep;188(17):6425-8. doi: 10.1128/JB.00427-06.
Abstract
Negative regulation of epr in Bacillus subtilis 168 is mediated jointly by both ScoC and SinR, which bind to their respective target sites 62 bp apart. Increasing the distance between the two sites abolishes repression, indicating that the two proteins interact, thereby suggesting a mechanism of corepression.
摘要
枯草芽孢杆菌168中epr的负调控由ScoC和SinR共同介导，它们结合在相距62 bp的各自靶位点上。增加两个位点之间的距离会消除抑制作用，这表明这两种蛋白质相互作用，从而提示了一种共抑制机制。
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