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[罗库溴铵所致严重过敏反应]

[Severe anaphylaxis from rocuronium].

作者信息

Kubitz J C, Krause T, Dietz R, Friederich P, Goetz A E

机构信息

Zentrum für Anästhesiologie und Intensivmedizin, Universitätsklinikum, Martinistrasse 52, 20246 Hamburg-Eppendorf.

出版信息

Anaesthesist. 2006 Nov;55(11):1169-71. doi: 10.1007/s00101-006-1074-8.

Abstract

Muscle relaxant drugs are the most frequent cause of anaphylactic and anaphylactoid reactions during anaesthesia. We report a case of a life-threatening anaphylactic reaction during induction of anaesthesia with severe bronchospasm as the first clinical symptom. Mechanical ventilation was nearly impossible. The patient required a multimodal antiallergic therapy and a high-dose catecholamine therapy for stabilization. Rocuronium was identified as the allergic agent using intradermal testing.

摘要

肌肉松弛药物是麻醉期间过敏反应和类过敏反应最常见的原因。我们报告一例在麻醉诱导期间发生的危及生命的过敏反应,首发临床症状为严重支气管痉挛。机械通气几乎无法进行。患者需要多模式抗过敏治疗和大剂量儿茶酚胺治疗以稳定病情。通过皮内试验确定罗库溴铵为过敏药物。

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